[HTML][HTML] Challenge of cancer in the elderly

C Marosi, M Köller - ESMO open, 2016 - Elsevier
Despite the sustained trend of decreasing overall cancer incidence, the number of elderly
patients with cancer will considerably increase in the coming years, as the incidence of …

Secular trends in incidence and mortality of bladder cancer in China, 1990–2017: a joinpoint and age-period-cohort analysis

X Liu, J Jiang, C Yu, Y Wang, Y Sun, J Tang, T Chen… - Cancer …, 2019 - Elsevier
Background Bladder cancer is closely related to occupational carcinogens, and China is
undergoing a rapid industrialization. However, trend of bladder cancer incidence and …

Management of bladder cancer in older patients

S Hatakeyama, S Narita, K Okita, T Narita… - Japanese journal of …, 2022 - academic.oup.com
Evidence has shown that patients with bladder cancer are diagnosed at a much older age
compared with those with other cancers. Given that co-morbidities and frailty are prevalent in …

Safety, tolerability, and preliminary efficacy of TAR-200 in patients with muscle-invasive bladder cancer who refused or were unfit for curative-intent therapy: a phase 1 …

MD Tyson, D Morris, J Palou, O Rodriguez… - The Journal of …, 2023 - auajournals.org
Purpose: Half of patients with muscle-invasive bladder cancer worldwide may not receive
curative-intent therapy. Elderly or frail patients are most affected by this unmet need. TAR …

Comparative perioperative outcomes in septuagenarians and octogenarians undergoing radical cystectomy for bladder cancer—do outcomes differ?

TD Haden, MC Prunty, AB Jones, CB Deroche… - European Urology …, 2018 - Elsevier
Background Treatment choice for muscle invasive bladder cancer continues to be radical
cystectomy. However, radical cystectomy carries a relatively high risk of morbidity and …

[HTML][HTML] Prognosis of patients with muscle invasive bladder cancer who are intolerable to receive any anti-cancer treatment

K Ogawa, Y Shimizu, S Uketa, N Utsunomiya… - Cancer Treatment and …, 2020 - Elsevier
Background The aim of this retrospective study was to evaluate the prognosis of patients
who had been diagnosed with muscle invasive bladder cancer (MIBC) and did not receive …

Bladder-sparing (chemo) radiotherapy in elderly patients with muscle-invasive bladder cancer: a retrospective cohort study

N Verschoor, WD Heemsbergen, JL Boormans… - Acta …, 2022 - Taylor & Francis
Background Organ-sparing treatment for muscle-invasive bladder cancer by maximal
transurethral removal of the tumor (TURB) followed by chemoradiation (CRT) has shown …

A pilot study of radiotherapy and local hyperthermia in elderly patients with muscle-invasive bladder cancers unfit for definitive surgery or chemoradiotherapy

NR Datta, E Stutz, E Puric, B Eberle, A Meister… - Frontiers in …, 2019 - frontiersin.org
Purpose: To present the outcomes of a pilot study with hyperthermia (HT) and radiotherapy
(RT) in elderly patients of muscle-invasive bladder cancers (MIBC) unfit for surgery or …

[HTML][HTML] Bladder preservation therapy in muscle-invasive bladder cancer: Current evidence and future perspectives

H Tanaka, T Kijima, Y Fujii - AME Medical Journal, 2020 - amj.amegroups.org
Radical cystectomy has been widely accepted as the standard treatment in muscle-invasive
bladder cancer. However, removal of the bladder requires urinary diversions and …

[HTML][HTML] Relationship of frailty with treatment modality selection in patients with muscle-invasive bladder cancer (FRART-BC study)

H Iwamura, S Hatakeyama, M Momota… - Translational …, 2021 - ncbi.nlm.nih.gov
Background We aimed to investigate the association of frailty with treatment selection in
patients with muscle-invasive bladder cancer (MIBC) as frailty is one of the key factors for …