Alzheimer's disease (AD) is pathologically defined by the presence of fibrillar amyloid β (Aβ)
peptide in extracellular senile plaques and tau filaments in intracellular neurofibrillary …

Multiple sclerosis (MS) is an autoimmune, inflammatory neurodegenerative disease of the
central nervous system characterized by demyelination and axonal damage. Diagnosis and …

Alzheimer's disease is a progressive, clinically heterogeneous, and particularly complex
neurodegenerative disease characterized by a decline in cognition. Over the last two …

HIV infected people are living longer due to the success of combined antiretroviral therapy
(cART). However, greater than 40-70% of HIV infected individuals develop HIV associated …

Osteopontin (OPN), a matricellular immunomodulatory cytokine highly expressed by
myelomonocytic cells, is known to regulate immune cell migration, communication, and …

BACKGROUND Central nervous system Langerhans cell histiocytosis (CNS‐LCH) brain
involvement may include mass lesions and/or a neurodegenerative disease (LCH‐ND) of …

As brain and bone disorders represent major health issues worldwide, substantial clinical
investigations demonstrated a bidirectional crosstalk on several levels, mechanistically …

Thymoquinone (TQ), the main pharmacological active ingredient within the black cumin
seed (Nigella sativa) is believed to be responsible for the therapeutic effects on chronic …

Bone, the major structural scaffold of the human body, has recently been demonstrated to
interact with several other organ systems through the actions of bone-derived cells and bone …

Introduction Osteopontin (OPN) is a phosphoglycoprotein with important roles in tissue
homeostasis, wound healing, immune regulation, and stress responses. It is expressed …