Aluminum and Alzheimer's disease: after a century of controversy, is there a plausible link?

L Tomljenovic - Journal of Alzheimer's Disease, 2011 - content.iospress.com
The brain is a highly compartmentalized organ exceptionally susceptible to accumulation of
metabolic errors. Alzheimer's disease (AD) is the most prevalent neurodegenerative disease …

Does neurotransmission impairment accompany aluminium neurotoxicity?

PP Gonçalves, VS Silva - Journal of Inorganic Biochemistry, 2007 - Elsevier
Neurobehavioral disorders, except their most overt form, tend to lie beyond the reach of
clinicians. Presently, the use of molecular data in the decision-making processes is limited …

Contamination and health risk assessment of lead, arsenic, cadmium, and aluminum from a total diet study of Jilin Province, China

B Wang, Y Liu, H Wang, L Cui, Z Zhang… - Food Science & …, 2020 - Wiley Online Library
Abstract Lead (Pb), arsenic (As), cadmium (Cd) and aluminum (Al) are the four most
common heavy metals and can cause serious harm to human health. To evaluate …

Can the mechanisms of aluminum neurotoxicity be integrated into a unified scheme?

MJ Strong, RM Garruto, JG Joshi… - Journal of Toxicology …, 1996 - Taylor & Francis
Regardless of the host, the route of administration, or the speciation, aluminum is a potent
neurotoxicant. In the young adult or developmentally mature host, the neuronal response to …

Aluminium-induced impairment of Ca2+ modulatory action on GABA transport in brain cortex nerve terminals

JM Cordeiro, VS Silva, CR Oliveira… - Journal of Inorganic …, 2003 - Elsevier
The γ-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in vertebrate CNS.
At GABAergic synapses, a high-affinity transporter exists, which is responsible for GABA …

Inhibition kinetics of human serum butyrylcholinesterase by Cd2+, Zn2+ and Al3+: comparison of the effects of metal ions on cholinesterases

B Sarkarati, AN Çokuğraş, EF Tezcan - Comparative Biochemistry and …, 1999 - Elsevier
Butyrylcholinesterase (BChE, EC 3.1. 1.8) has been purified about 6600-fold from human
serum with a procedure including ammonium sulfate fractionation (55–70%) with acid step …

[PDF][PDF] Effect of ions on the activity of brain acetylcholinesterase from tropical fish

CRD Assis, AG Linhares, VM Oliveira… - Journal of Coastal Life …, 2015 - academia.edu
Objective: To investigate the effect of ions on brain acetylcholinesterase (AChE; EC 3.1. 1.7)
activities from economic important fish [pirarucu, Arapaima gigas; tambaqui, Colossoma …

Acetylcholinesterase activity in the Mongolian gerbil brain after acute poisoning with aluminum

DV Micic, ND Petronijevic - Journal of Alzheimer's Disease, 2000 - content.iospress.com
The aim of the present study was to evaluate the acetylcholinesterase activity in the brain of
adult gerbils (Meriones unguiculatus) treated with aluminum. AlCl 3× 6H 2 O was given “per …

Speciation of aluminium in human serum investigated by HPLC/high resolution inductively coupled plasma mass spectrometry (HR-ICP-MS): Effects of sialic acid …

MH Nagaoka, T Maitani - Journal of health science, 2009 - jstage.jst.go.jp
Aluminium (Al) in the blood is bound to transferrin (Tf), a glycoprotein of about 80 kDa that is
characterized by its need for a synergistic anion. The binding affinity of both Al and iron (Fe) …

铝对大鼠大脑皮层和海马神经细胞钙浓度影响

任锐, 李百祥, 张旸, 张晓峰, 高淑英 - 中国公共卫生, 2004 - zgggws.com
中国CPH Page 1 [ J] . Med Sci sportsexerc, 1997, 71( 8) : 992- 998. 1142 Vincent J. The
potential value and toxicity of chromium picolinate as a nutritional supplement, weight loss …