Simple Summary Currently, there is no treatment that can cure patients with late stage
metastatic prostate cancer. Prostate-specific membrane antigen is a type of protein …

Targeted alpha therapy is an oncological treatment, where cytotoxic doses of alpha radiation
are locally delivered to tumor cells, while the surrounding healthy tissue is minimally …

A search in PubMed revealed that 72 radionuclides have been considered for molecular or
functional targeted radionuclide therapy. As radionuclide therapies increase in number and …

Compton imaging exploits inelastic scattering, known as Compton scattering, using a
Compton camera consisting of a scatterer detector in the front layer and an absorber …

Purpose This review discusses the current state of prostate-specific membrane antigen
(PSMA)-based alpha therapy of metastatic castration-resistant prostate cancer (mCRPC) …

The use of radiopharmaceutical therapies (RPTs) in the treatment of cancers is growing
rapidly, with more agents becoming available for clinical use in last few years and many new …

The concept of personalized medicine has been steadily growing for the past decades.
Monoclonal antibodies (mAbs) are undoubtedly playing an important role in the transition …

Abstract Background Lead-212 (212Pb) is a promising radionuclide for targeted therapy, as
it decays to α-particle emitter bismuth-212 (212Bi) via β-particle emission. This extends the …

Metabolic processes or specific receptors serve as targets for the design of appropriate
radiopharmaceuticals. The principle of “theranostics,” in the context of nuclear medicine (Fig …

Both hardware and software developments have seen single photon emission CT
(SPECT)/X-ray CT technology grow at a rapid rate. Such growth has been fuelled by the …