Comparative analysis of the protective effects of melatonin and vitamin E on streptozocin‐induced diabetes mellitus

G Baydas, H Canatan, A Turkoglu - Journal of pineal research, 2002 - Wiley Online Library
There is a clearly documented link between diabetic complications and lipid peroxidation.
Hyperglycemia causes a reduction in levels of protective endogenous antioxidants and …

A review of neuroprotective agents

MS Levi, MA Brimble - Current medicinal chemistry, 2004 - ingentaconnect.com
The brain remains an area where little corrective surgery can be performed and the reversal
of damage is almost impossible. Recently, reports of agents offering neuroprotection have …

Daily rhythm of glutathione peroxidase activity, lipid peroxidation and glutathione levels in tissues of pinealectomized rats

G Baydas, MF Gursu, S Yilmaz, S Canpolat, A Yasar… - Neuroscience …, 2002 - Elsevier
Melatonin is a component of the antioxidant defense system since it has radical scavenging
and antioxidant activities. In the present study, we aimed to investigate the endogenous …

Melatonin protects the central nervous system of rats against toluene-containing thinner intoxication by reducing reactive gliosis

G Baydas, RJ Reiter, VS Nedzvetskii, A Yaşar, M Tuzcu… - Toxicology letters, 2003 - Elsevier
Neuroprotective effects of melatonin against free radical damage have been studied
extensively. Thinner containing 60–70% toluene is a neurotoxic mixture which is widely …

Effects of melatonin on plasma oxidative stress in rats with streptozotocin induced diabetes

N Klepac, Z Rudeš, R Klepac - Biomedicine & pharmacotherapy, 2006 - Elsevier
The aim of this study was to evaluate the effect of single melatonin injection on plasma
oxidative stress in rats with streptozotocin induced diabetes. Diabetes was induced after a …

A novel role for melatonin: regulation of the expression of cell adhesion molecules in the rat hippocampus and cortex

G Baydas, VS Nedzvetsky, PA Nerush, SV Kirichenko… - Neuroscience …, 2002 - Elsevier
Neural cell adhesion molecules (NCAMs) are members of the immunoglobulin superfamily
and are involved in synaptic rearrangements in the mature brain. There are three major …

Effects of certain micronutrients and melatonin on plasma lipid, lipid peroxidation, and homocysteine levels in rats

G Baydas, O Yilmaz, S Celik, A Yasar… - Archives of Medical …, 2002 - Elsevier
BACKGROUND: Numerous studies suggest an association between high intake of
antioxidant vitamins and fish oil and reduced risk of coronary heart disease …

Altered glial fibrillary acidic protein content and its degradation in the hippocampus, cortex and cerebellum of rats exposed to constant light: reversal by melatonin

G Baydas, RJ Reiter, VS Nedzvetskii… - Journal of pineal …, 2002 - Wiley Online Library
Reactive astrocytosis is a well‐known phenomenon that occurs rapidly after physical or
metabolic injury to the brain. One of the important events during astrocyte differentiation is …

Insulin increases homocysteine levels in a dose-dependent manner in diabetic rats

MF Gursu, G Baydas, G Cikim, H Canatan - Archives of Medical Research, 2002 - Elsevier
BACKGROUND: Even moderate increases in levels of homocysteine cause cardiovascular
degeneration. Various genetic and nutritional factors affect plasma homocysteine …

[PDF][PDF] Pre-and post-treatment of streptozocin administered rats with melatonin: effects on some hepatic enzymes of carbohydrate metabolism

M Akmali, R Ahmadi, M VESAL - 2010 - sid.ir
Background: Melatonin, found in high concentrations in the pineal gland, organs within the
digestive system and in some plants and fungi, acts as an antioxidant which decreases …