Neurological associations of COVID-19

MA Ellul, L Benjamin, B Singh, S Lant… - The Lancet …, 2020 - thelancet.com
Background The COVID-19 pandemic, caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), is of a scale not seen since the 1918 influenza pandemic …

The genetics of multiple sclerosis: from 0 to 200 in 50 years

SE Baranzini, JR Oksenberg - Trends in genetics, 2017 - cell.com
Multiple sclerosis (MS) is a common autoimmune disease that targets myelin in the central
nervous system (CNS). Multiple genome-wide association studies (GWAS) over the past 10 …

Immunology of multiple sclerosis

M Sospedra, R Martin - Seminars in neurology, 2016 - thieme-connect.com
Multiple sclerosis (MS) is considered a prototypic autoimmune disease of the central
nervous system (CNS). A complex genetic background with the HLA-DR15 haplotype as the …

Current multiple sclerosis treatments have improved our understanding of MS autoimmune pathogenesis

R Martin, M Sospedra, M Rosito… - European journal of …, 2016 - Wiley Online Library
Multiple sclerosis (MS) is the most common inflammatory disorder of the central nervous
system (CNS) in young adults. When MS is not treated, it leads to irreversible and severe …

CD8 T cell-mediated killing of orexinergic neurons induces a narcolepsy-like phenotype in mice

R Bernard-Valnet, L Yshii, C Quériault… - Proceedings of the …, 2016 - National Acad Sciences
Narcolepsy with cataplexy is a rare and severe sleep disorder caused by the destruction of
orexinergic neurons in the lateral hypothalamus. The genetic and environmental factors …

High-dimensional single-cell analysis reveals the immune signature of narcolepsy

FJ Hartmann, R Bernard-Valnet, C Quériault… - Journal of experimental …, 2016 - rupress.org
Narcolepsy type 1 is a devastating neurological sleep disorder resulting from the destruction
of orexin-producing neurons in the central nervous system (CNS). Despite its striking …

Neuroprotective panel of olive polyphenols: Mechanisms of action, anti-demyelination, and anti-stroke properties

T Grubić Kezele, B Ćurko-Cofek - Nutrients, 2022 - mdpi.com
Neurological diseases such as stroke and multiple sclerosis are associated with high
morbidity and mortality, long-term disability, and social and economic burden. Therefore …

Advances in treatment of progressive multifocal leukoencephalopathy

R Bernard‐Valnet, IJ Koralnik… - Annals of …, 2021 - Wiley Online Library
Progressive multifocal encephalopathy (PML) is a severe demyelinating disease of the
central nervous system (CNS) caused by JC virus (JCV), which occurs in …

Exploring the use of dimethyl fumarate as microglia modulator for neurodegenerative diseases treatment

M Rosito, C Testi, G Parisi, B Cortese, P Baiocco… - Antioxidants, 2020 - mdpi.com
The maintenance of redox homeostasis in the brain is critical for the prevention of the
development of neurodegenerative diseases. Drugs acting on brain redox balance can be …

Treatment with mesenchymal-derived extracellular vesicles reduces injury-related pathology in pyramidal neurons of monkey perilesional ventral premotor cortex

M Medalla, W Chang, SM Calderazzo… - Journal of …, 2020 - Soc Neuroscience
Functional recovery after cortical injury, such as stroke, is associated with neural circuit
reorganization, but the underlying mechanisms and efficacy of therapeutic interventions …