An insight into advances in developing nanotechnology based therapeutics, drug delivery, diagnostics and vaccines: multidimensional applications in tuberculosis …

H Chopra, YK Mohanta, PR Rauta, R Ahmed… - Pharmaceuticals, 2023 - mdpi.com
Tuberculosis (TB), one of the deadliest contagious diseases, is a major concern worldwide.
Long-term treatment, a high pill burden, limited compliance, and strict administration …

[HTML][HTML] Nanoparticle-based drug delivery systems in inhaled therapy: improving respiratory medicine

E Cojocaru, OR Petriș, C Cojocaru - Pharmaceuticals, 2024 - mdpi.com
Inhaled nanoparticle (NP) therapy poses intricate challenges in clinical and
pharmacodynamic realms. Recent strides have revolutionized NP technology by enabling …

Colchicine mesoporous silica nanoparticles/hydrogel composite loaded cotton patches as a new encapsulator system for transdermal osteoarthritis management

AL Mohamed, H Elmotasem, AAA Salama - International Journal of …, 2020 - Elsevier
Colchicine is a drug from the past with a bright shining future. It has gained much attention
nowadays due to the newly explored therapeutic avenues that were opened by its …

Nano-based anti-tubercular drug delivery: an emerging paradigm for improved therapeutic intervention

B Nabi, S Rehman, S Aggarwal, S Baboota… - Drug Delivery and …, 2020 - Springer
Tuberculosis (TB) classified as one of the most fatal contagious diseases is of prime concern
globally. Mycobacterium tuberculosis is the causative agent that ingresses within the host …

Mannosylation of budesonide palmitate nanoprodrugs for improved macrophage targeting

LP Do Nascimento, N Tsapis, F Reynaud… - European Journal of …, 2022 - Elsevier
In a strategy to improve macrophage targeting of glucocorticoids (GCs) for anti-inflammatory
therapy, a so-called nanoprodrug of budesonide palmitate decorated by mannose moieties …

Mannose receptor and targeting strategies

P Jahagirdar, AS Lokhande, P Dandekar… - … drug delivery by …, 2019 - Springer
The mannose family receptors are unique multidomain, multifunctional endocytic receptors
belonging to the C-type lectin family. These receptors, although structurally similar, exhibit …

Mannosylated gelatin nanoparticles enhanced inactivated PRRSV targeting dendritic cells and increased T cell immunity

J Huang, H Liu, M Wang, X Bai, J Cao, Z Zhang… - Veterinary Immunology …, 2021 - Elsevier
The objective of the present work was to evaluate the efficacy of a novel antigen carrier
using mannosylated gelatin nanoparticles with entrapped inactivated porcine reproductive …

In-vitro and ex-vivo characterization of novel mannosylated gelatin nanoparticles of linezolid by quality-by-design approach

KD Patil, SB Bagade, SC Bonde - Journal of Drug Delivery Science and …, 2020 - Elsevier
The present study was aimed to develop and characterize novel linezolid (LNZ) loaded
mannosylated gelatin nanoparticles (Mn-GNPs) using the Quality by Design (QbD) …

[HTML][HTML] Breaking barriers: The potential of nanosystems in antituberculosis therapy

CSC Canales, JIM Cazorla, RMM Cazorla… - Bioactive Materials, 2024 - Elsevier
Tuberculosis (TB), caused by Mycobacterium tuberculosis, continues to pose a significant
threat to global health. The resilience of TB is amplified by a myriad of physical, biological …

Nebulized, macrophage-targeted, Linezolid-loaded lipid carriers for intracellular treatment of tubercular infections–In vitro/in vivo study

S Makled, N Nafee, H Okasha, N Boraie - Journal of Drug Delivery Science …, 2024 - Elsevier
Effective treatment of tuberculosis (TB) demands progression control in line with TB
elimination. The objective herein is to formulate nebulized targeted antitubercular-lipid …