Integrated analysis of circulating cell free nucleic acids for cancer genotyping and immune phenotyping of tumor microenvironment

M Chaddha, H Rai, R Gupta, D Thakral - Frontiers in Genetics, 2023 - frontiersin.org
The circulating cell-free nucleic acids (ccfNAs) consist of a heterogenous cocktail of both
single (ssNA) and double-stranded (dsNA) nucleic acids. These ccfNAs are secreted into the …

[HTML][HTML] Extracellular Vesicles as Drug Delivery System for Cancer Therapy

J Wang, B Yin, J Lian, X Wang - Pharmaceutics, 2024 - mdpi.com
In recent decades, the pursuit of drug delivery systems has led to the development of
numerous synthetic options aimed at enhancing drug efficacy while minimizing side effects …

Structure characterization and immunological activity of capsular polysaccharide from live and heat-killed Lacticaseibacillus paracasei 6235

Y Wang, R Liu, Z Xie, L Du, Y Wang, J Han… - International Journal of …, 2024 - Elsevier
Capsular polysaccharide (CPS) as a probiotic component has the ability to regulate the
function of the host's immune system. However, how the structure and function of heat-killed …

Exploring the cell-free total RNA transcriptome in diffuse large B-cell lymphoma and primary mediastinal B-cell lymphoma patients as biomarker source in blood …

P Decruyenaere, E Giuili, K Verniers, J Anckaert… - Frontiers in …, 2023 - frontiersin.org
Introduction Diffuse large B-cell lymphoma (DLBCL) and primary mediastinal B-cell
lymphoma (PMBCL) are aggressive histological subtypes of non-Hodgkin's lymphoma …

[HTML][HTML] Characterizing the Cell-Free Transcriptome in a Humanized Diffuse Large B-Cell Lymphoma Patient-Derived Tumor Xenograft Model for RNA-Based Liquid …

P Decruyenaere, W Daneels, A Morlion… - International Journal of …, 2024 - mdpi.com
The potential of RNA-based liquid biopsy is increasingly being recognized in diffuse large B-
cell lymphoma (DLBCL), the most common subtype of non-Hodgkin's lymphoma. This study …

[HTML][HTML] Decoding bioactive signals of the RNA secretome: the cell-free messenger RNA catalogue

RE De Sota, SR Quake, JJ Sninsky… - Expert Reviews in …, 2024 - ncbi.nlm.nih.gov
Despite gene-expression profiling being one of the most common methods to evaluate
molecular dysregulation in tissues, the utilization of cell-free messenger RNA (cf-mRNA) as …

A Comprehensive Review on Circulating cfRNA in Plasma: Implications for Disease Diagnosis and Beyond

P Zhong, L Bai, M Hong, J Ouyang, R Wang, X Zhang… - Diagnostics, 2024 - mdpi.com
Circulating cfRNA in plasma has emerged as a fascinating area of research with potential
applications in disease diagnosis, monitoring, and personalized medicine. Circulating RNA …

Transcriptome profiling of cerebrospinal fluid in Alzheimer's Disease reveals molecular dysregulations associated with disease

RE De Sota, SJ Khoury, J Zhuang, RA Rissman… - medRxiv, 2023 - medrxiv.org
Despite the increasing prevalence of neurodegenerative diseases, the molecular
characterization of the brain remains challenging due to limited access to the tissue …