About 280 million people suffer from depression as the most common neurological disorder
and the most common cause of death worldwide. Exercise with serotonin released in the …

The orexin-A/hypocretin-1 and orexin-B/hypocretin-2 are neuropeptides synthesized by a
cluster of neurons in the lateral hypothalamus and perifornical area. Orexin neurons receive …

Physical exercise may improve cognitive function by modulating molecular and cellular
mechanisms within the brain. We propose that the facilitation of long-term synaptic …

In the present article, we provide a review of current knowledge regarding the role played by
physical activity (PA) in preventing age-related cognitive decline and reducing risk of …

The neuropeptides orexins are important in regulating the neurobiological systems that
respond to stressful stimuli. Furthermore, orexins are known to play a role many of the …

In the present article, we provide a brief review of current knowledge regarding the effects
induced by physical exercise on hippocampus. Research involving animals and humans …

Non-alcoholic steatohepatitis (NASH) occasionally occurs under obesity; however, factors
modulating the natural history of fatty liver disease remain unknown. Since hypothalamic …

Objective Polycystic ovary syndrome (PCOS) is characterized by phenotypic heterogeneity
and has a wide variety of consequences. Approximately half of women with PCOS are …

The beneficial effects of exercise on the proper functioning of the body have been firmly
established. Multi-systemic metabolic regulation of exercise is the consequence of …

Ageing is defined as a time-dependent functional decline that occurs in most of live
organisms. Brain modification during the ageing process has been considered to …