[HTML][HTML] Cervical cancer therapies: Current challenges and future perspectives

CA Burmeister, SF Khan, G Schäfer, N Mbatani… - Tumour Virus …, 2022 - Elsevier
Cervical cancer is the fourth most common female cancer worldwide and results in over 300
000 deaths globally. The causative agent of cervical cancer is persistent infection with high …

The management of locally advanced cervical cancer

PN Ch, L Gurram, S Chopra… - Current opinion in …, 2018 - journals.lww.com
Advanced imaging modalities are increasingly being utilized to tailor treatments.
Neoadjuvant chemotherapy followed by surgery does not improve outcomes in FIGO Stage …

Radiation therapy for cervical cancer: executive summary of an ASTRO clinical practice guideline

J Chino, CM Annunziata, S Beriwal, L Bradfield… - Practical radiation …, 2020 - Elsevier
Purpose This guideline reviews the evidence and provides recommendations for the
indications and appropriate techniques of radiation therapy (RT) in the treatment of …

Finding an easy way to harmonize: a review of advances in clinical research and combination strategies of EZH2 inhibitors

C Li, Y Wang, Y Gong, T Zhang, J Huang, Z Tan… - Clinical …, 2021 - Springer
Enhancer of zeste homolog 2 inhibitors (EZH2i) have garnered increased attention owing to
their anticancer activity by targeting EZH2, a well-known cancer-promoting factor. However …

Risk factors and a prediction model for lower limb lymphedema following lymphadenectomy in gynecologic cancer: a hospital-based retrospective cohort study

K Kuroda, Y Yamamoto, M Yanagisawa, A Kawata… - BMC women's …, 2017 - Springer
Background Lower limb lymphedema (LLL) is a chronic and incapacitating condition
afflicting patients who undergo lymphadenectomy for gynecologic cancer. This study aimed …

British Gynaecological Cancer Society (BGCS) cervical cancer guidelines: recommendations for practice

N Reed, J Balega, T Barwick, L Buckley… - European Journal of …, 2021 - Elsevier
Cervix cancer in many countries is declining and screening programmes and immunisation
will reduce the incidence in the next few decades. This guideline attempts to cover …

Cervical cancer: evaluation and management

J Wipperman, T Neil, T Williams - American family physician, 2018 - aafp.org
Human papillomavirus infection is the precursor for the development of cervical cancer and
is detectable in 99.7% of squamous cell carcinoma and adenocarcinoma cases. Early …

Growth arrest‐specific 5 attenuates cisplatin‐induced apoptosis in cervical cancer by regulating STAT3 signaling via miR‐21

T Yao, R Lu, J Zhang, X Fang, L Fan… - Journal of Cellular …, 2019 - Wiley Online Library
Cervical cancer is the most common cause of female cancer‐related mortality worldwide.
Decreased expression of long noncoding RNA growth arrest‐specific 5 (GAS5) is found in …

[HTML][HTML] Systemic therapy for cervical carcinoma–current status

K Serkies, J Jassem - Chinese Journal of Cancer Research, 2018 - ncbi.nlm.nih.gov
Two major treatment modalities in cervical cancer are radiation therapy (RT) and surgery.
Chemotherapy continues to be the main form of systemic therapy adjunctive to definitive …

[HTML][HTML] Application and reflection of genomic scar assays in evaluating the efficacy of platinum salts and PARP inhibitors in cancer therapy

R Gou, H Dong, B Lin - Life Sciences, 2020 - Elsevier
Defective DNA repair is one of the most important features of tumors. BRCA1/2 participates
in homologous recombination repair as a key tumor suppressor gene. BRCA1/2 mutation is …