Wiskott‐Aldrich syndrome (WAS) is a rare X‐linked primary immunodeficiency characterized
by microthrombocytopenia, eczema, recurrent infections, and an increased incidence of …

Abstract The Wiskott-Aldrich syndrome (WAS) is a rare X-linked disorder originally described
by Dr. Alfred Wiskott in 1937 and Dr. Robert Aldrich in 1954 as a familial disease …

Endometriosis (EM) is a chronic disease characterized by the presence and proliferation of
functional endometrial glands and stroma outside the uterine cavity. Ovaries and pelvic …

With an array of activating and inhibitory receptors, natural killer (NK) cells can specifically
eradicate infected and transformed cells. Target cell killing is achieved through directed …

A female offspring of consanguineous parents, showed features of Wiskott-Aldrich syndrome
(WAS), including recurrent infections, eczema, thrombocytopenia, defective T cell …

Natural killer (NK) cells are innate lymphoid cells, which play key roles in elimination of
virally infected and malignant cells. The balance between activating and inhibitory signals …

BACKGROUND: Dedicator of cytokinesis 8 (DOCK8) mutations are responsible for a rare
primary combined immunodeficiency syndrome associated with severe cutaneous viral …

Natural killer (NK) cells are innate immune lymphocytes that recognize and kill cancer and
infected cells, which makes them unique 'off-the-shelf'candidates for a new generation of …

Immunoactinopathies caused by mutations in actin‐related proteins are a growing group of
inborn errors of immunity (IEI). Immunoactinopathies are caused by a dysregulated actin …

Wiskott‐Aldrich syndrome (WAS) is a rare X‐linked recessive primary immunodeficiency
characterised by immune dysregulation, microthrombocytopaenia, eczema and lymphoid …