Ischemic stroke caused by arterial occlusion is the most common type of stroke, which is
among the most frequent causes of disability and death worldwide. Current treatment …

Ferroptosis is a new kind of regulated cell death that is characterized by highly iron-
dependent lipid peroxidation. Ferroptosis involves various biology processes, such as iron …

Ferroptosis is a recently identified, iron-regulated, non-apoptotic form of cell death. It is
characterized by cellular accumulation of lipid reactive oxygen species that ultimately leads …

Functional failure of tau contributes to age-dependent, iron-mediated neurotoxicity, and as
iron accumulates in ischemic stroke tissue, we hypothesized that tau failure may exaggerate …

Ischemic stroke is one of the major causes of morbidity and mortality, affecting millions of
people worldwide. Inevitably, the interruption of cerebral blood supply after ischemia may …

Abstract Ischemia/reperfusion (I/R) is a pathological process that occurs in numerous organs
throughout the human body, and it is frequently associated with severe cellular damage and …

Ischemic stroke (IS) accounts for more than 80% of the total stroke, which represents the
leading cause of mortality and disability worldwide. Cerebral ischemia/reperfusion injury …

Ferroptosis is a form of regulated cell death that is mainly triggered by iron-dependent lipid
peroxidation. A growing body of evidence suggests that ferroptosis is involved in the …

Ischemia-reperfusion (I/R) injury is a major challenge in perioperative medicine that
contributes to pathological damage in various conditions, including ischemic stroke …

Infections are a leading cause of death in stroke patients. In a mouse model of focal cerebral
ischemia, we tested the hypothesis that a stroke-induced immunodeficiency increases the …