The reservoir of latent HIV

J Chen, T Zhou, Y Zhang, S Luo, H Chen… - Frontiers in cellular …, 2022 - frontiersin.org
The persistence of latent reservoir of the human immunodeficiency virus (HIV) is currently
the major challenge in curing HIV infection. After HIV infects the human body, the latent HIV …

Milk-derived extracellular vesicles in inter-organism, cross-species communication and drug delivery

R Sanwlani, P Fonseka, SV Chitti, S Mathivanan - Proteomes, 2020 - mdpi.com
Milk is considered as more than a source of nutrition for infants and is a vector involved in
the transfer of bioactive compounds and cells. Milk contains abundant quantities of …

Exosomes in pathogen infections: a bridge to deliver molecules and link functions

W Zhang, X Jiang, J Bao, Y Wang, H Liu… - Frontiers in …, 2018 - frontiersin.org
Exosomes are extracellular vesicles derived from cell endocytosis which act as transmitters
between cells. They are composed of proteins, lipids, and RNAs through which they …

Important role of microglia in HIV-1 associated neurocognitive disorders and the molecular pathways implicated in its pathogenesis

A Borrajo, C Spuch, MA Penedo, JM Olivares… - Annals of …, 2021 - Taylor & Francis
The development of effective combined anti-retroviral therapy (cART) led to a significant
reduction in the death rate associated with human immunodeficiency virus type 1 (HIV-1) …

Exosomes serve as novel modes of tick-borne flavivirus transmission from arthropod to human cells and facilitates dissemination of viral RNA and proteins to the …

W Zhou, M Woodson, B Neupane, F Bai… - PLoS …, 2018 - journals.plos.org
Molecular determinants and mechanisms of arthropod-borne flavivirus transmission to the
vertebrate host are poorly understood. In this study, we show for the first time that a cell line …

The exosome: a review of current therapeutic roles and capabilities in human reproduction

M Dimik, P Abeysinghe, J Logan, M Mitchell - Drug Delivery and …, 2023 - Springer
Abstract Exosomes are nano-vesicles (30–150 nm) which may be useful as therapeutic
delivery vehicles and as diagnostic biomarkers. Exosomes are produced naturally within the …

Roles of exosomes in ocular diseases

J Liu, F Jiang, Y Jiang, Y Wang, Z Li, X Shi… - International journal …, 2020 - Taylor & Francis
Exosomes, nanoscale vesicles with a diameter of 30 to 150 nm, are composed of a lipid
bilayer, protein, and genetic material. Exosomes are secreted by virtually all types of cells in …

Mechanisms underlying HIV-associated cognitive impairment and emerging therapies for its management

RJ Ellis, MJ Marquine, M Kaul, JA Fields… - Nature Reviews …, 2023 - nature.com
People living with HIV are affected by the chronic consequences of neurocognitive
impairment (NCI) despite antiretroviral therapies that suppress viral replication, improve …

MicroRNAs and exosomes: key players in HIV pathogenesis

J Sadri Nahand, F Bokharaei‐Salim… - HIV …, 2020 - Wiley Online Library
Objectives HIV infection is well known to cause impairment of the human immune system,
and until recently was a leading cause of death. It has been shown that T lymphocytes are …

Large-scale, cross-flow based isolation of highly pure and endocytosis-competent extracellular vesicles

RP McNamara, CP Caro-Vegas… - Journal of …, 2018 - Taylor & Francis
Isolation of extracellular vesicles (EVs) from cell culture supernatant or plasma can be
accomplished in a variety of ways. Common measures to quantify relative success are …