Objectives Organ-specific hemosiderosis and iron overload complications are more serious
and more frequent in some patients with beta thalassemia major (BTM) compared with …

Frequency of hereditary hemochromatosis gene mutations and their effects on iron overload
among beta thalassemia patients of Che Page 1 AIMS Molecular Science, 8(4): 233–247. DOI …

Iron loading is regarded as the primary cause of endocrine abnormalities in thalassemia
major patients. Thus, the purpose of the current research was to explore the impact of …

Objectives: To evaluate any association between the frequency of hereditary
hemochromatosis (HFE) gene mutation (H63D and C282Y) and iron overload in beta …

Introduction Mutations in the HFE gene have been shown to be associated with
hemochromatosis which is observed in beta-thalassemia major. In this study, we determined …

地中海贫血是一种常见的常染色体隐性遗传病, 是由某个或多个珠蛋白基因异常引起一种或一种
以上珠蛋白肽链合成减少或缺乏的溶血性贫血. 地中海贫血长期的慢性溶血 …

BACKGROUND: β-thalassemia major (βTM) is a genetic disorder characterized by a
deficiency in hemoglobin production, ineffective erythropoiesis, chronic hemolysis, lifelong …

Background: Co-inheritance of hemochromatosis (HFE) gene mutations may play an
essential role in the pathogenesis of iron overload in beta-thalassemia major (BTM) patients …

Hemochromatosis in a β‐thalassemia minor patient with H63D homozygous mutation: A case
report - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage …

Background: Iron overload (serum ferritin> 1000ng/ml) occurs in patients with sickle cell
anaemia (SCA) and it is often linked to red cell transfusions and genetic mutations …