Small molecules in the treatment of COVID-19

S Lei, X Chen, J Wu, X Duan, K Men - Signal transduction and targeted …, 2022 - nature.com
The outbreak of COVID-19 has become a global crisis, and brought severe disruptions to
societies and economies. Until now, effective therapeutics against COVID-19 are in high …

Targeting epidermal growth factor receptor signalling pathway: A promising therapeutic option for COVID‐19

A Razzaq, C Disoma, Y Zhou, S Tao… - Reviews in Medical …, 2024 - Wiley Online Library
The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is continuously
producing new variants, necessitating effective therapeutics. Patients are not only …

Finding novel AMPs secreted from the human microbiome as potent antibacterial and antibiofilm agents and studying their synergistic activity with Ag NCs

A Singh, A Amod, V Mulpuru, N Mishra… - ACS Applied Bio …, 2023 - ACS Publications
Due to the enhanced resistance of bacteria to antibiotics, researchers always try to find
effective alternatives to treat drug-resistant bacterial infections. In this context, we have …

Exploration of selected monoterpenes as potential TRPC channel family modulator in lung cancer, an in-silico upshot

A Singh, A Mishra, A Meena, N Mishra… - Journal of Biomolecular …, 2023 - Taylor & Francis
Lung cancer is still the most frequent cause of cancer-related death, accounting for nearly
two million cases yearly. As cancer is a multifactorial disease, developing novel molecular …

Regulating pri/pre-microRNA up/down expressed in cancer proliferation, angiogenesis and metastasis using selected potent triterpenoids

A Mathur, A Singh, Y Hussain, A Mishra… - International Journal of …, 2024 - Elsevier
MicroRNAs (miRNAs) play a crucial role in cancer progression by selectively inducing
translational degradation of messenger RNA (mRNA) via sequence-specific interactions …

Identification of naturally occurring compounds as alternatives to radiation therapy for treatment of small cell lung cancer: Natural alternatives to radiation therapy for …

MS Pingali, A Singh, A Anurag Anand… - Journal of …, 2023 - Taylor & Francis
Radiation resistance is one of the major problems in the treatment of small cell lung cancer
(SCLC). Most of these patients are given radiation as first-line treatment and it was observed …

Omics data analysis reveals common molecular basis of small cell lung cancer and COVID-19

KMS Andalib, A Ahmed, A Habib - Journal of Biomolecular …, 2023 - Taylor & Francis
The impact of COVID-19 infection on individuals with small cell lung cancer (SCLC) poses a
serious threat. Unfortunately, the molecular basis of this severe comorbidity has yet to be …

Identification of coastal pesticide pollutants as potent inhibitors of Bacillus pasteurii urease mediated calcium carbonate precipitation: a computational approach

A Ganapathy Vilasam Sreekala, KK Gupta… - Journal of …, 2023 - Taylor & Francis
Microbially induced calcite precipitation (MICP) through urease enzyme has attained a lot of
recognition in various fields of civil engineering and geotechnology for stabilizing the …

Marine-Derived Cytosine Arabinoside (Ara-C) Inhibits Biofilm Formation by Inhibiting PEL Operon Proteins (Pel A and Pel B) of Pseudomonas aeruginosa: An In …

S Datta, V Singh, S Nag, DN Roy - Molecular Biotechnology, 2024 - Springer
Pseudomonas aeruginosa (P. aeruginosa) is a gram-negative biofilm-forming opportunistic
human pathogen whose vital mechanism is biofilm formation for better survival. PelA and …

[HTML][HTML] A review on in silico virtual screening methods in COVID-19 using anticancer drugs and other natural/chemical inhibitors

B Sokouti - Exploration of Targeted Anti-tumor Therapy, 2023 - ncbi.nlm.nih.gov
The present coronavirus disease 2019 (COVID-19) pandemic scenario has posed a difficulty
for cancer treatment. Even under ideal conditions, malignancies like small cell lung cancer …