Next-generation sequencing technologies have revolutionarily advanced sequence-based
research with the advantages of high-throughput, high-sensitivity, and high-speed. RNA-seq …

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MicroRNAs are a class of non-coding small RNAs involved in the negative regulation of
gene expression, which play critical roles in developmental and metabolic pathways …

We show that RNA editing sites can be called with high confidence using RNA sequencing
data from multiple samples across either individuals or species, without the need for …

Post-transcriptional modifications have been recently expanded with the addition of RNA
editing, which is predominantly mediated by adenosine and cytidine deaminases acting on …

RNA editing by cytidine (C) to uridine (U) conversions is widespread in plant mitochondria
and chloroplasts. In some plant taxa,“reverse” U-to-C editing also occurs. However, to date …

The reliable detection of RNA editing sites from massive sequencing data remains
challenging and, although several methodologies have been proposed, no computational …

RNA editing enhances the diversity of gene products at the post-transcriptional level.
Approaches for genome-wide identification of RNA editing face two main challenges …

RNA editing is a widespread post-transcriptional mechanism able to modify transcripts
through insertions/deletions or base substitutions. It is prominent in mammals, in which …

Multi-drug resistance is increasing at alarming rates. The efficacy of phage therapy, treating
bacterial infections with bacteriophages alone or in combination with traditional antibiotics …