The endocannabinoid system: a potential target for the treatment of various diseases
H Lowe, N Toyang, B Steele, J Bryant… - International journal of …, 2021 - mdpi.com
The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a
balance in internal environment (temperature, mood, and immune system) and energy input …
balance in internal environment (temperature, mood, and immune system) and energy input …
Diversity in chemical structures and biological properties of plant alkaloids
S Bhambhani, KR Kondhare, AP Giri - Molecules, 2021 - mdpi.com
Phytochemicals belonging to the group of alkaloids are signature specialized metabolites
endowed with countless biological activities. Plants are armored with these naturally …
endowed with countless biological activities. Plants are armored with these naturally …
Synthetic opioids: a review and clinical update
A Shafi, AJ Berry, H Sumnall… - Therapeutic …, 2022 - journals.sagepub.com
The term 'opioids' refers to both the natural compounds ('opiates') which are extracted from
the opium poppy plant (Papaver somniferum) and their semi-synthetic and synthetic …
the opium poppy plant (Papaver somniferum) and their semi-synthetic and synthetic …
Electrical stimulation for therapeutic approach
Electrical stimulation as a therapeutic approach is widely applicable in terms of target
tissues or target effects. This method can be an alternative to conventional therapies for …
tissues or target effects. This method can be an alternative to conventional therapies for …
[HTML][HTML] Users' Acceptability and Perceived Efficacy of mHealth for Opioid Use Disorder: Scoping Review
Background The opioid crisis continues to pose significant challenges to global public
health, necessitating the development of novel interventions to support individuals in …
health, necessitating the development of novel interventions to support individuals in …
Evaluating the clinical benefit of brain-computer interfaces for control of a personal computer
A Fry, HW Chan, NY Harel, LA Spielman… - Journal of Neural …, 2022 - iopscience.iop.org
Brain-computer interfaces (BCIs) enabling the control of a personal computer could provide
myriad benefits to individuals with disabilities including paralysis. However, to realize this …
myriad benefits to individuals with disabilities including paralysis. However, to realize this …
Physical therapists' role in solving the opioid epidemic
PE Mintken, JR Moore, TW Flynn - journal of orthopaedic & sports physical …, 2018 - jospt.org
An estimated 116 million Americans suffer from chronic pain, at a cost of over
600billionperyear,orroughly 2000 per person per year. In this Viewpoint, the authors …
600billionperyear,orroughly 2000 per person per year. In this Viewpoint, the authors …
Opioid-induced neuroanatomical, microglial and behavioral changes are blocked by suvorexant without diminishing opioid analgesia
R McGregor, MF Wu, TC Thannickal, S Li… - Nature Mental …, 2024 - nature.com
Heroin use disorder in humans and chronic opioid administration to mice result in an
increase in the number and a decrease in the size of detected hypocretin (Hcrt, or orexin) …
increase in the number and a decrease in the size of detected hypocretin (Hcrt, or orexin) …
Opiate anticipation, opiate induced anatomical changes in hypocretin (Hcrt, orexin) neurons and opiate induced microglial activation are blocked by the dual Hcrt …
R McGregor, MF Wu, TC Thannickal, JM Siegel - bioRxiv, 2024 - pmc.ncbi.nlm.nih.gov
We previously found that heroin addiction in humans is accompanied by an increase in the
number of detected Hcrt neurons and a decrease in their soma size. We now show that the …
number of detected Hcrt neurons and a decrease in their soma size. We now show that the …
[HTML][HTML] Implementing a novel statewide network to support emergency department-initiated buprenorphine treatment
BM Clemency, RA Hoopsick, SJ Burnett… - Western Journal of …, 2022 - ncbi.nlm.nih.gov
Methods Using the PRECEDE-PROCEED implementation science framework, we provide
an overview of the creation of the MATTERS network in Western New York. We also include …
an overview of the creation of the MATTERS network in Western New York. We also include …