Effects of air pollution on cellular senescence and skin aging

I Martic, P Jansen-Dürr, M Cavinato - Cells, 2022 - mdpi.com
The human skin is exposed daily to different environmental factors such as air pollutants and
ultraviolet (UV) light. Air pollution is considered a harmful environmental risk to human skin …

Human skin responses to environmental pollutants: a review of current scientific models

R Fitoussi, MO Faure, G Beauchef, S Achard - Environmental Pollution, 2022 - Elsevier
Whatever the exposure route, chemical, physical and biological pollutants modify the whole
organism response, leading to nerve, cardiac, respiratory, reproductive, and skin system …

[HTML][HTML] Long-term blue light exposure impairs mitochondrial dynamics in the retina in light-induced retinal degeneration in vivo and in vitro

L Wang, X Yu, D Zhang, Y Wen, L Zhang, Y Xia… - … of Photochemistry and …, 2023 - Elsevier
Long-term light exposure, especially in the spectrum of blue light, frequently causes
excessive oxidative stress in dry age-related macular degeneration (AMD). Here, to gain …

Iron derived from NCOA4-mediated ferritinophagy causes cellular senescence via the cGAS-STING pathway

HY Li, TT Wei, M Zhuang, CY Tan, TH Xie, J Cai… - Cell Death …, 2023 - nature.com
Cellular senescence is a hallmark of aging and has been linked to age-related diseases.
Age-related macular degeneration (AMD), the most common aging-related retinal disease …

[HTML][HTML] 3D models currently proposed to investigate human skin aging and explore preventive and reparative approaches: A descriptive review

F Lombardi, FR Augello, A Ciafarone, V Ciummo… - Biomolecules, 2024 - mdpi.com
Skin aging is influenced by intrinsic and extrinsic factors that progressively impair skin
functionality over time. Investigating the skin aging process requires thorough research …

Metformin inactivates the cGAS-STING pathway through autophagy and suppresses senescence in nucleus pulposus cells

C Ren, J Jin, C Li, J Xiang, Y Wu, Y Zhou… - Journal of Cell …, 2022 - journals.biologists.com
Intervertebral disc degeneration (IVDD) is a complex process involving many factors, among
which excessive senescence of nucleus pulposus cells is considered to be the main factor …

Inhibition of Klf10 attenuates oxidative stress-induced senescence of chondrocytes via modulating mitophagy

J Shang, N Lin, R Peng, N Jiang, B Wu, B Xing, S Lin… - Molecules, 2023 - mdpi.com
Osteoarthritis (OA) is the most prevalent degenerative joint disease in the elderly.
Accumulation of evidence has suggested that chondrocyte senescence plays a significant …

FGF2, LIF, and IGF-1 supplementation improves mouse oocyte in vitro maturation via increased glucose metabolism

A Nahar, J Becker, R Pasquariello… - Biology of …, 2024 - academic.oup.com
Chemically defined oocyte maturation media supplemented with FGF2, LIF, and IGF-1 (FLI
medium) enabled significantly improved oocyte quality in multiple farm animals, yet the …

The tumor suppressor SOCS1 diminishes tolerance to oxidative stress in hepatocellular carcinoma

A Shukla, MGM Khan, AA Cayarga, M Namvarpour… - Cancers, 2024 - mdpi.com
Simple Summary SOCS1 functions as a tumor suppressor in liver cancer and in many other
cancers, but the underlying mechanisms are not yet completely understood. Using mice …

Potential role of ergothioneine rich mushroom as anti-aging candidate through elimination of neuronal senescent cells

Y Apparoo, CW Phan, UR Kuppusamy, EWC Chan - Brain Research, 2024 - Elsevier
Oxidative stress can upset the antioxidant balance and cause accelerated aging including
neurodegenerative diseases and decline in physiological function. Therefore, an antioxidant …