Nuclear localization signal-tagged systems: Relevant nuclear import principles in the context of current therapeutic design

R Goswami, A Gupta, O Bednova… - Chemical Society …, 2024 - pubs.rsc.org
Nuclear targeting of therapeutics provides a strategy for enhancing efficacy of molecules
active in the nucleus and minimizing off-target effects.'Active'nuclear-directed transport and …

[HTML][HTML] Development and challenges of cells-and materials-based tooth regeneration

Z Fu, Y Zhuang, J Cui, R Sheng, H Tomás… - Engineered …, 2022 - Elsevier
Tooth defect and loss are common clinical diseases in stomatology. With the extension of life
expectancy, there is an increasing demand for tooth tissue and whole tooth regeneration …

Nucleic acid drugs: recent progress and future perspectives

X Sun, S Setrerrahmane, C Li, J Hu, H Xu - Signal Transduction and …, 2024 - nature.com
High efficacy, selectivity and cellular targeting of therapeutic agents has been an active area
of investigation for decades. Currently, most clinically approved therapeutics are small …

Advanced materials and technologies for oral diseases

H Cui, Y You, GW Cheng, Z Lan, KL Zou… - … and Technology of …, 2023 - Taylor & Francis
Oral disease, as a class of diseases with very high morbidity, brings great physical and
mental damage to people worldwide. The increasing burden and strain on individuals and …

[HTML][HTML] May carriers at nanoscale improve the Endodontic's future?

P Diogo, MAF Faustino, PJ Palma, A Rai… - Advanced Drug Delivery …, 2023 - Elsevier
Nanocarriers (NCs) are dynamic nanovehicles used to transport bioactive derivatives like
therapeutical formulations, drugs and/or dyes. The current review assists in understanding …

Stimuli-controllable iron oxide nanoparticle assemblies: Design, manipulation and bio-applications

LE Low, HP Lim, YS Ong, SP Siva, CS Sia… - Journal of Controlled …, 2022 - Elsevier
Despite its wide establishment over the years, iron oxide nanoparticle (IONP) still draws
extensive interest in the biomedical fields due to its biocompatibility, biodegradability …

[HTML][HTML] Injectable Xenogeneic Dental Pulp Decellularized Extracellular Matrix Hydrogel Promotes Functional Dental Pulp Regeneration

S Yuan, X Yang, X Wang, J Chen, W Tian… - International Journal of …, 2023 - mdpi.com
The present challenge in dental pulp tissue engineering scaffold materials lies in the
development of tissue-specific scaffolds that are conducive to an optimal regenerative …

Recent development and advances on polysaccharide composite scaffolds for dental and dentoalveolar tissue regeneration

X Wang, H Li, M Mu, R Ye, L Zhou, G Guo - Polymer Reviews, 2024 - Taylor & Francis
Oral diseases are a prevalent global issue, causing significant health and economic
burdens that greatly diminish the quality of life for affected individuals. Tissue engineering …

Decellularized rat submandibular gland as an alternative scaffold for dental pulp regeneration

Y Shi, Y Wang, Z Shan, Z Gao - Frontiers in Bioengineering and …, 2023 - frontiersin.org
Introduction: Decellularized extracellular matrix has been recognized as an optimal scaffold
for dental pulp regeneration. However, the limited amount of native dental pulp tissue …

Engineering of Bioresorbable Polymers for Tissue Engineering and Drug Delivery Applications

M Dobrzyńska‐Mizera, JM Dodda, X Liu… - Advanced …, 2024 - Wiley Online Library
Herein, the recent advances in the development of resorbable polymeric‐based
biomaterials, their geometrical forms, resorption mechanisms, and their capabilities in …