Pulmonary hypertension (PH) is a serious disease characterized by various degrees of
pulmonary vasoconstriction and progressive fibroproliferative remodeling and inflammation …

The tumor microenvironment (TME) is a complex macromolecular network filled with a series
of stromal cells. It plays an important role in tumorigenesis, development, immune escape …

Piezo is a mechanosensitive cation channel responsible for stretch-mediated Ca2+ and Na+
influx in multiple types of cells. Little is known about the functional role of Piezo1 in the lung …

Idiopathic pulmonary arterial hypertension (PAH) is a fatal and progressive disease.
Sustained vasoconstriction due to pulmonary arterial smooth muscle cell (PASMC) …

Staphylococcus aureus is a pulmonary pathogen associated with substantial human
morbidity and mortality. As vaccines targeting virulence determinants have failed to be …

Pulmonary hypertension (PH) is a chronic and fatal disease, for which new therapeutic
drugs and approaches are needed urgently. Baicalein and baicalin, the active compounds …

Concentric pulmonary vascular wall thickening due partially to increased pulmonary artery
(PA) smooth muscle cell (PASMC) proliferation contributes to elevating pulmonary vascular …

Immune abnormality involves in various diseases, such as infection, allergic diseases,
autoimmune diseases, as well as transplantation. Several signal pathways have been …

Colorectal cancer (CRC) is the third most common malignant tumor in the world, and it is
prone to recurrence and metastasis during treatment. Aerobic glycolysis is one of the main …

Abstract Study Objectives Chronic obstructive pulmonary disease and obstructive sleep
apnea overlap syndrome is associated with excess mortality, and outcomes are related to …