Genetically encoded fluorescent biosensors have revolutionized the study of cell signaling
and metabolism, as they allow for live-cell measurements with high spatiotemporal …

In vivo fluorescence recording techniques have produced landmark discoveries in
neuroscience, providing insight into how single cell and circuit-level computations mediate …

Optical approaches to monitor neural activity are transforming neuroscience, owing to a fast-
evolving palette of genetically encoded molecular reporters. However, the field still requires …

Neuromodulators transform animal behaviors. Recent research has demonstrated the
importance of both sustained and transient change in neuromodulators, likely due to tonic …

Bioelectricity is the electrical activity that occurs within living cells and tissues. This activity is
critical for regulating homeostatic cellular function and communication, and disruptions of …

A central goal of neuroscience is to understand how the brain transforms external stimuli
and internal bodily signals into patterns of activity that underlie cognition, emotional states …

Plethora of research has shed light on the critical role of synaptic dysfunction in various
neurodegenerative disorders (NDDs), including Alzheimer's disease (AD), Parkinson's …

Optical sensors have transformed the field of neuromodulation because neuromodulator
dynamics are essential for their function. Despite their high spatial and temporal resolution …

Glutamate is one of the most important excitatory neurotransmitters within the mammalian
central nervous system. The role of glutamate in regulating neural network signaling …

Neurobiologists widely use green genetically encoded calcium indicators (GECIs) for
visualization of neuronal activity. Among them, ratiometric GECIs allow imaging of both …