Lung cancer mortality is strongly associated with the predominant diagnosis of late stage
lesions that hampers effective therapy. Molecular biomarkers for early lung cancer detection …

Esophageal squamous cell carcinoma (ESCC) is among the most common malignancies,
but little is known about its spatial intratumoral heterogeneity (ITH) and temporal clonal …

Despite the advances in treatment using chemotherapy or targeted therapies, due to static
survival rates, non-small cell lung cancer (NSCLC) is the major cause of cancer-related …

A major cause of oxaliplatin chemoresistance in colorectal cancer (CRC) is acquired
epithelial-mesenchymal transition (EMT) in cancer cells, making the cancer cells easy to …

Asbestos is a naturally occurring mineral consisting of extremely fine fibres that can become
trapped in the lungs after inhalation. Occupational and environmental exposures to asbestos …

Hydroquinone (HQ), one of the most important metabolites derived from benzene, is known
to be associated with acute myelogenous leukemia (AML) risk, however, its carcinogenic …

Cancer gene discovery is reliant on distinguishing driver mutations from a multitude of
passenger mutations in tumour genomes. While driver genes may be revealed based on …

The term 'personalized medicine'refers to a medical procedure that consists in the grouping
of patients based on their predicted individual response to therapy or risk of disease. In …

It is now widely accepted that cancer is caused by complex interactions between genetic
and epigenetic factors and the environment. Only in the last 20 years, DNA methylation has …

Background: Renal cell carcinoma (RCC) is one of the most common human cancers. Clear
cell renal cell carcinoma (ccRCC) is a major subtype of RCC. However, the molecular …