Sjögren syndrome or Sjögren disease is a chronic form of autoimmune epithelitis
characterized by lymphocytic infiltration of the exocrine glands, particularly the salivary and …

Decorin is an extracellular matrix protein that belongs to the family of small leucine‐rich
proteoglycans. As a matrix protein, the first discovered role of decorin is participating in …

Objective Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease, and its
pathogenetic mechanism is far from being understood. In this study, we aimed to explore the …

The human microbiome plays an important role in autoimmune diseases. However, there is
limited knowledge regarding the microbiota in individuals with primary Sjögren's syndrome …

Sjögren's syndrome (SS) is an autoimmune disorder characterized by mononuclear cell
infiltration in the exocrine glands, which leads to sicca syndrome (xerostomia and …

Metformin is an oral antihyperglycemic drug widely used to treat type 2 diabetes, acting via
indirect activation of 5′ Adenosine Monophosphate-activated Protein Kinase (AMPK) …

There are some challenges and unmet needs in the early diagnosis and management of
Sjögren's syndrome (SjS) such as prominent glandular dysfunction at diagnosis and long …

Background Environmental etiology of primary Sjögren's syndrome (pSS), an autoimmune
disease, has been proposed. This study determined whether the exposure to air pollutants …

Extraglandular manifestations (EGMs) in primary Sjogren's syndrome (pSS) represent the
clinical expression of the systemic involvement in this disease. EGMs are characterized by a …

Abstract Background Activated T and B cells participate in the development and progression
of Sjögren's syndrome (SS). Metformin, a first-line anti-diabetic drug, exerts anti …