Osteoporosis is common in human immunodeficiency virus (HIV)–infected persons. The
etiology of osteoporosis in HIV-infected patients is likely multifactorial, involving traditional …

Fragility fracture is a worldwide problem and a main cause of disability and impaired quality
of life. It is primarily caused by osteoporosis, characterized by impaired bone quantity and or …

HIV mainly replicates in CD4þ T lymphocytes and monocyte/macrophages causing severe
immunological impairment. In addition to the immune system, HIV infection affects tissues …

Apart from mediating viral entry, the function of the free HIV-1 envelope protein (gp120) has
yet to be elucidated. Our group previously showed that EP2 derived from one β-strand in …

Dysregulation of the bone marrow niche resulting from the direct and indirect effects of HIV
infection contributes to haematological abnormalities observed in HIV patients. The bone …

To maintain bone mass turnover and bone mineral density (BMD), bone marrow (BM)
mesenchymal stem cells (MSC s) are constantly recruited and subsequently differentiated …

The human immunodeficiency virus type 1 (HIV)/AIDS pandemic represents the most
significant global health challenge in modern history. This infection leads toward an …

Several HIV‐1 infected patients show bone loss and osteopenia/osteoporosis during the
course of disease. The mechanisms underlying this degenerative process are largely …

Objective: We studied changes in bone mineral density (BMD) and bone turnover after
initiation of combination antiretroviral therapy (cART) and the contribution of …

Inflammation and immune activation have been thrust to center stage in the understanding
of HIV-1 disease pathogenesis and progression. Early work demonstrated that heightened …