The etiology of preeclampsia

E Jung, R Romero, L Yeo, N Gomez-Lopez… - American journal of …, 2022 - Elsevier
Preeclampsia is one of the “great obstetrical syndromes” in which multiple and sometimes
overlapping pathologic processes activate a common pathway consisting of endothelial cell …

Syncytiotrophoblast stress in preeclampsia: the convergence point for multiple pathways

CWG Redman, AC Staff, JM Roberts - American journal of obstetrics and …, 2022 - Elsevier
Preeclampsia evolves in 2 stages: a placental problem that generates signals to the mother
to cause a range of responses that comprise the second stage (preeclampsia syndrome) …

[HTML][HTML] FIGO (international Federation of Gynecology and obstetrics) initiative on fetal growth: best practice advice for screening, diagnosis, and management of fetal …

N Melamed, A Baschat, Y Yinon… - … of Gynaecology and …, 2021 - ncbi.nlm.nih.gov
Fetal growth restriction (FGR) is defined as the failure of the fetus to meet its growth potential
due to a pathological factor, most commonly placental dysfunction. Worldwide, FGR is a …

Analysis of SARS-CoV-2 vertical transmission during pregnancy

C Fenizia, M Biasin, I Cetin, P Vergani, D Mileto… - Nature …, 2020 - nature.com
The impact of SARS-CoV-2 infection during gestation remains unclear. Here, we analyse the
viral genome on maternal and newborns nasopharyngeal swabs, vaginal swabs, maternal …

Maternal-fetal inflammation in the placenta and the developmental origins of health and disease

JA Goldstein, K Gallagher, C Beck, R Kumar… - Frontiers in …, 2020 - frontiersin.org
Events in fetal life impact long-term health outcomes. The placenta is the first organ to form
and is the site of juxtaposition between the maternal and fetal circulations. Most diseases of …

The immunobiology of preterm labor and birth: intra-amniotic inflammation or breakdown of maternal–fetal homeostasis

N Gomez-Lopez, J Galaz, D Miller… - …, 2022 - rep.bioscientifica.com
In brief The syndrome of preterm labor comprises multiple established and novel etiologies.
This review summarizes the distinct immune mechanisms implicated in preterm labor and …

[HTML][HTML] Endometritis: new time, new concepts

K Kitaya, T Takeuchi, S Mizuta, H Matsubayashi… - Fertility and sterility, 2018 - Elsevier
Endometritis is subdivided into two categories. Acute endometritis is symptomatic and
characterized by microabscess formation and neutrophil invasion in the endometrial …

The fetal origins of mental illness

BJS Al-Haddad, E Oler, B Armistead… - American journal of …, 2019 - Elsevier
The impact of infections and inflammation during pregnancy on the developing fetal brain
remains incompletely defined, with important clinical and research gaps. Although the …

The pivotal role of the placenta in normal and pathological pregnancies: a focus on preeclampsia, fetal growth restriction, and maternal chronic venous disease

MA Ortega, O Fraile-Martínez, C García-Montero… - Cells, 2022 - mdpi.com
The placenta is a central structure in pregnancy and has pleiotropic functions. This organ
grows incredibly rapidly during this period, acting as a mastermind behind different fetal and …

[HTML][HTML] SARS-CoV-2 placentitis, stillbirth, and maternal COVID-19 vaccination: clinical–pathologic correlations

DA Schwartz, SB Mulkey, DJ Roberts - American journal of obstetrics and …, 2023 - Elsevier
Stillbirth is a recognized complication of COVID-19 in pregnant women that has recently
been demonstrated to be caused by SARS-CoV-2 infection of the placenta. Multiple global …