[HTML][HTML] Bisindole Compounds—Synthesis and Medicinal Properties
M Marinescu - Antibiotics, 2024 - mdpi.com
The indole nucleus stands out as a pharmacophore, among other aromatic heterocyclic
compounds with remarkable therapeutic properties, such as benzimidazole, pyridine …
compounds with remarkable therapeutic properties, such as benzimidazole, pyridine …
Structure and Interactions of HIV-1 gp41 CHR-NHR Reverse Hairpin Constructs Reveal Molecular Determinants of Antiviral Activity
L He, R McAndrew, R Barbu, G Gifford… - Journal of Molecular …, 2024 - Elsevier
Engineered reverse hairpin constructs containing a partial C-heptad repeat (CHR)
sequence followed by a short loop and full-length N-heptad repeat (NHR) were previously …
sequence followed by a short loop and full-length N-heptad repeat (NHR) were previously …
Targeting a Conserved Lysine in the Hydrophobic Pocket of HIV-1 gp41 Improves Small Molecule Antiviral Activity
L He, G Zhou, V Sofiyev, E Garcia, N Nguyen, KH Li… - Viruses, 2022 - mdpi.com
Human Immunodeficiency virus (HIV-1) fusion is mediated by glycoprotein-41, a protein that
has not been widely exploited as a drug target. Small molecules directed at the gp41 …
has not been widely exploited as a drug target. Small molecules directed at the gp41 …
The Synthesis of 2, 2-BIS (1-INDOL-3-YL) Acenaphthylene-1 (2)-Ones Using Nanocatalysis: Fluorescent Sensing for Cu Ions
2, 2-bis (1H-indol-3-yl) acenaphthylene-1 (2H)-ones were synthesised by the reaction of
acenaphthenequinone and 2 equivalents of indole using Fe3O4@ SiO2@ Si-Pr-NH …
acenaphthenequinone and 2 equivalents of indole using Fe3O4@ SiO2@ Si-Pr-NH …
Novel 2-alkylthio-1-benzylimidazole-5-carboxylic Acid Derivatives Targeting Gp41: Design, Synthesis, and In Vitro Anti-HIV Activity Evaluation
T Mostashari-Rad, S Claes, D Schols… - Current HIV …, 2022 - ingentaconnect.com
Background: Although current available medications have increased the quality of life in HIV-
infected patients, there are still some shortcomings in HIV treatment arising from viral …
infected patients, there are still some shortcomings in HIV treatment arising from viral …
[PDF][PDF] The Synthesis of 2, 2-bis (1-indol-3-yl) acenaphthylene-1 (2)-ones using nanocatalysis: Fluorescent sensing for Cu2+ ions
2, 2-bis (1H-indol-3-yl) acenaphthylene-1 (2H)-ones were synthesised by the reaction of
acenaphthenequinone and 2 equivalents of indole using Fe3O4@ SiO2@ Si-Pr-NH …
acenaphthenequinone and 2 equivalents of indole using Fe3O4@ SiO2@ Si-Pr-NH …
[引用][C] Targeting a Conserved Lysine in the Hydrophobic Pocket of HIV-1 gp41 Improves Small Molecule Antiviral Activity. Viruses 2022, 14, 2703
L He, G Zhou, V Sofiyev, E Garcia, N Nguyen, KH Li… - 2022 - europepmc.org
Human Immunodeficiency virus (HIV-1) fusion is mediated by glycoprotein-41, a protein that
has not been widely exploited as a drug target. Small molecules directed at the gp41 …
has not been widely exploited as a drug target. Small molecules directed at the gp41 …