Extracellular vesicles (EVs) are complex lipid membrane vehicles with variable expressions
of molecular cargo, composed of diverse subpopulations that participate in the intercellular …

Cell therapies have emerged as a promising new class of “living” therapeutics over the last
decade and have been particularly successful for treating hematological malignancies …

Cells secrete numerous bioactive molecules that are essential for the function of healthy
organisms. However, scalable methods are needed to link individual cell secretions to their …

The secreted products of cells drive many functions in vivo; however, methods to link this
functional information to surface markers and transcriptomes have been lacking. By …

The ability to selectively bind to antigenic peptides and secrete effector molecules can
define rare and low-affinity populations of cells with therapeutic potential in emerging T cell …

Single-cell encapsulation in droplets has become a powerful tool in immunotherapy,
medicine discovery, and single-cell analysis, thanks to its capability for cell confinement in …

Structured microparticles, with unique shapes, customizable sizes, multiple materials, and
spatially-defined chemistries, are leading the way for emerging 'lab on a …

From “Lab on a Chip” to “Lab on a Particle”. The miniaturization and automation of life
science laboratory operations has leveraged fabrication advances in the integrated circuit …

Monoclonal antibodies are increasingly used to prevent and treat viral infections and are
pivotal in pandemic response efforts. Antibody-secreting cells (ASCs; plasma cells and …

The separation of specific cell populations is instrumental in gaining insights into cellular
processes, elucidating disease mechanisms, and advancing applications in tissue …