[HTML][HTML] Current status of therapeutic approaches against peripheral nerve injuries: a detailed story from injury to recovery

G Hussain, J Wang, A Rasul, H Anwar… - … journal of biological …, 2020 - ncbi.nlm.nih.gov
Peripheral nerve injury is a complex condition with a variety of signs and symptoms such as
numbness, tingling, jabbing, throbbing, burning or sharp pain. Peripheral nerves are fragile …

Influence of the neuroprotective properties of quercetin on regeneration and functional recovery of the nervous system

SOM Fideles, A de Cássia Ortiz, DV Buchaim… - Antioxidants, 2023 - mdpi.com
Quercetin is a dietary flavonoid present in vegetables, fruits, and beverages, such as onions,
apples, broccoli, berries, citrus fruits, tea, and red wine. Flavonoids have antioxidant and anti …

Quercetin: a bioactive compound imparting cardiovascular and neuroprotective benefits: scope for exploring fresh produce, their wastes, and by-products

IUH Bhat, R Bhat - Biology, 2021 - mdpi.com
Simple Summary The present review summarizes the generated hypothesis and critical role
of quercetin in cardiovascular and neuroprotective diseases reported over the last decade …

[HTML][HTML] Suppression of TRPV1/TRPM8/P2Y nociceptors by withametelin via downregulating MAPK signaling in mouse model of vincristine-induced neuropathic pain

A Khan, B Shal, AU Khan, R Ullah, MW Baig… - International journal of …, 2021 - mdpi.com
Vincristine (VCR) is a widely used chemotherapy drug that induced peripheral painful
neuropathy. Yet, it still lacks an ideal therapeutic strategy. The transient receptor potential …

Silencing of circRNA. 2837 plays a protective role in sciatic nerve injury by sponging the miR-34 family via regulating neuronal autophagy

Z Zhou, Y Niu, G Huang, J Lu, A Chen, L Zhu - Molecular Therapy-Nucleic …, 2018 - cell.com
Circular RNAs (circRNAs) represent a class of non-coding RNAs that are involved in
transcriptional and posttranscriptional gene expression regulation and associated with …

Neuroprotective mechanism of Ajugarin-I against Vincristine-Induced neuropathic pain via regulation of Nrf2/NF-κB and Bcl2 signalling

A Khan, B Shal, AU Khan, KU Shah, SS Zahra… - International …, 2023 - Elsevier
Vincristine (VCR) is a well-known chemotherapeutic agent that frequently triggers
neuropathic pain. Ajugarin-I (Aju-I) isolated from Ajuga bracteosa exerts antioxidant, anti …

Battery‐Free, Wireless, Cuff‐Type, Multimodal Physical Sensor for Continuous Temperature and Strain Monitoring of Nerve

S Kim, YS Oh, K Lee, S Kim, WY Maeng, KS Kim… - Small, 2023 - Wiley Online Library
Peripheral nerve injuries cause various disabilities related to loss of motor and sensory
functions. The treatment of these injuries typically requires surgical operations for improving …

Chitosan nanoparticles loaded with Foeniculum vulgare extract regulate retrieval of sensory and motor functions in mice

MA Bajaber, A Hameed, G Hussain, R Noreen… - Heliyon, 2024 - cell.com
In this study, chitosan nanoparticles (CSNPs) encapsulating Foeniculum vulgare (FV) seed
extract (SE) were prepared for the controlled delivery of bioactive phytoconstituents. The …

Low-intensity low-frequency pulsed ultrasound ameliorates sciatic nerve dysfunction in a rat model of cisplatin-induced peripheral neuropathy

B Bilir-Yildiz, FB Sunay, HF Yilmaz, O Bozkurt-Girit - Scientific Reports, 2022 - nature.com
Chemotherapy-induced peripheral neuropathy is a neurological complication that frequently
occurs during chemotherapeutic intervention, resulting in damaged myelin sheath, motor …

Comparative neuroprotective effects of Cerebrolysin, dexamethasone, and ascorbic acid on sciatic nerve injury model: behavioral and histopathological study

HM Elhessy, OA Habotta, M Eldesoqui… - Frontiers in …, 2023 - frontiersin.org
Background The majority of the suggested experimental modalities for peripheral nerve
injury (PNI) result in varying degrees of recovery in animal models; however, there are not …