Feeding, hunger, satiety and serotonin in invertebrates

AJ Tierney - Proceedings of the Royal Society B, 2020 - royalsocietypublishing.org
The serotonergic modulation of feeding behaviour has been intensively studied in several
invertebrate groups, including Arthropoda, Annelida, Nematoda and Mollusca. These …

A review of the bioeffects of low-intensity focused ultrasound and the benefits of a cellular approach

MN Collins, KA Mesce - Frontiers in physiology, 2022 - frontiersin.org
This review article highlights the historical developments and current state of knowledge of
an important neuromodulation technology: low-intensity focused ultrasound. Because …

Neural circuit regulation by identified modulatory projection neurons

DM Blitz - Frontiers in Neuroscience, 2023 - frontiersin.org
Rhythmic behaviors (eg, walking, breathing, and chewing) are produced by central pattern
generator (CPG) circuits. These circuits are highly dynamic due to a multitude of input they …

Cell anatomy and network input explain differences within but not between leech touch cells at two different locations

S Meiser, JM Sleeboom, I Arkhypchuk… - Frontiers in Cellular …, 2023 - frontiersin.org
Mechanosensory cells in the leech share several common features with mechanoreceptors
in the human glabrous skin. Previous studies showed that the six T (touch) cells in each …

Transcriptomic profiling and the first spatial expression analysis of candidate genes in the salivary gland of the East Asian medicinal leech, Hirudo nipponia

JH Kim, CJ Lee, YS Yu, YP Aryal, S Kim, JY Suh… - Developmental & …, 2024 - Elsevier
Hirudo nipponia, a blood-sucking leech native to East Asia, possesses a rich repertoire of
active ingredients in its saliva, showcasing significant medical potential due to its …

Spatio-Temporal Changes of Extracellular Matrix (ECM) Stiffness in the Development of the Leech Hirudo verbana

L Pulze, N Baranzini, T Congiu, F Acquati… - International Journal of …, 2022 - mdpi.com
The invertebrate leech Hirudo verbana represents a powerful experimental animal model for
improving the knowledge about the functional interaction between the extracellular matrix …

Transcriptional profiling of identified neurons in leech

E Heath-Heckman, S Yoo, C Winchell, M Pellegrino… - BMC genomics, 2021 - Springer
Background While leeches in the genus Hirudo have long been models for neurobiology,
the molecular underpinnings of nervous system structure and function in this group remain …

The medicinal leech as a valuable model for better understanding the role of a TLR4-like receptor in the inflammatory process

R Girardello, N Baranzini, M Molteni, C Rossetti… - Cell and tissue …, 2019 - Springer
Despite extensive investigation focused on both the molecular characteristics and the
expression level of Toll-like receptors (TLRs) during the inflammatory response in …

[HTML][HTML] Acceleration of genome rearrangement in clitellate annelids

DT Schultz, EAC Heath-Heckman, CJ Winchell… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Comparisons of multiple metazoan genomes have revealed the existence of ancestral
linkage groups (ALGs), genomic scaffolds sharing sets of orthologous genes that have been …

Small steps and larger strides in understanding the neural bases of crawling in the medicinal leech

KA Mesce, M Newhoff - The Neural Control of Movement, 2020 - Elsevier
The nervous system of the medicinal leech (Hirudo species) has often provided elegant
solutions to long-standing questions in the field of locomotor control. Such outcomes stem …