Ph-like acute lymphoblastic leukemia
Philadelphia chromosome–like acute lymphoblastic leukemia (Ph-like ALL) is a newly
identified high-risk (HR) B-lineage ALL subtype, accounting for∼ 15% of children with …
identified high-risk (HR) B-lineage ALL subtype, accounting for∼ 15% of children with …
Genomic characterization of paediatric acute lymphoblastic leukaemia: an opportunity for precision medicine therapeutics
SK Tasian, SP Hunger - British journal of haematology, 2017 - Wiley Online Library
Major advances in genetic and epigenetic profiling of acute lymphoblastic leukaemia (ALL)
have enhanced the understanding of key biological subsets of de novo and relapsed ALL …
have enhanced the understanding of key biological subsets of de novo and relapsed ALL …
Potent efficacy of combined PI3K/mTOR and JAK or ABL inhibition in murine xenograft models of Ph-like acute lymphoblastic leukemia
SK Tasian, DT Teachey, Y Li, F Shen… - Blood, The Journal …, 2017 - ashpublications.org
Philadelphia chromosome (Ph)–like B-cell acute lymphoblastic leukemia (Ph-like ALL) is
associated with activated JAK/STAT, Abelson kinase (ABL), and/or phosphatidylinositol 3 …
associated with activated JAK/STAT, Abelson kinase (ABL), and/or phosphatidylinositol 3 …
Genomics and pharmacogenomics of pediatric acute lymphoblastic leukemia
C Wu, W Li - Critical reviews in oncology/hematology, 2018 - Elsevier
Acute lymphoblastic leukaemia (ALL) is a prevalent form of pediatric cancer that accounts for
70–80% of all leukemias. Genome-based analysis, exome sequencing, transcriptomics and …
70–80% of all leukemias. Genome-based analysis, exome sequencing, transcriptomics and …
Survival among children diagnosed with acute lymphoblastic leukemia in the United States, by race and age, 2001 to 2009: findings from the CONCORD‐2 study
EW Tai, KC Ward, A Bonaventure, DA Siegel… - Cancer, 2017 - Wiley Online Library
BACKGROUND Acute lymphoblastic leukemia (ALL) is the most common childhood
malignancy. This report describes the survival of children with ALL in the United States using …
malignancy. This report describes the survival of children with ALL in the United States using …
New targeted therapies for relapsed pediatric acute lymphoblastic leukemia
J Pierro, LE Hogan, T Bhatla… - Expert review of …, 2017 - Taylor & Francis
Introduction: The improvement in outcomes for children with acute lymphoblastic leukemia
(ALL) is one of the greatest success stories of modern oncology however the prognosis for …
(ALL) is one of the greatest success stories of modern oncology however the prognosis for …
Genomics and precision medicine for clinicians and scientists in hypertension
Dominiczak et al Genomics and Precision Medicine e11 descent. 16 Similar to previous
studies, 66 SNP genetic risk scores were significantly associated with target organ damage …
studies, 66 SNP genetic risk scores were significantly associated with target organ damage …
Mechanism of co-operation of mutant IL-7Rα and mutant NRAS in acute lymphoblastic leukemia: role of MYC
H Winer, W Li, G Rodrigues, T Gower… - …, 2023 - pmc.ncbi.nlm.nih.gov
Acute lymphoblastic leukemia (ALL) is an aggressive leukemia which can be derived from
either T-cell or B-cell precursors. With current treatments, the survival rate is high, but the …
either T-cell or B-cell precursors. With current treatments, the survival rate is high, but the …
Integrating RNA-seq and scRNA-seq to explore the biological significance of NAD+ metabolism-related genes in the initial diagnosis and relapse of childhood B-cell …
C Lin, JQ Xu, GC Zhong, H Chen, HM Xue… - Frontiers in …, 2022 - frontiersin.org
Background Nicotinamide Adenine Dinucleotide (NAD) depletion is reported to be a
potential treatment for B-cell Acute Lymphoblastic Leukemia (B-ALL), but the mechanism of …
potential treatment for B-cell Acute Lymphoblastic Leukemia (B-ALL), but the mechanism of …
Cannabinoid CP55940 selectively induces apoptosis in Jurkat cells and in ex vivo T-cell acute lymphoblastic leukemia through H2O2 signaling mechanism
V Soto-Mercado, M Mendivil-Perez… - Leukemia Research, 2020 - Elsevier
T-cell acute lymphoblastic leukemia (T-ALL) is a highly heterogeneous malignant
hematological disorder arising from T-cell progenitors. This study was aimed to evaluate the …
hematological disorder arising from T-cell progenitors. This study was aimed to evaluate the …