[HTML][HTML] From NAFLD to HCC: Advances in noninvasive diagnosis

Q Xu, M Feng, Y Ren, X Liu, H Gao, Z Li, X Su… - Biomedicine & …, 2023 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) has gradually become one of the major liver
health problems in the world. The dynamic course of the disease goes through steatosis …

Immunomodulation in non-alcoholic fatty liver disease: exploring mechanisms and applications

Z Guo, Q Wu, P Xie, J Wang, W Lv - Frontiers in Immunology, 2024 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) exhibits increased lipid enrichment in
hepatocytes. The spectrum of this disease includes stages such as nonalcoholic simple fatty …

Tumor Microenvironment–Activated Nanostructure to Enhance MRI Capability and Nanozyme Activity for Highly Tumor‐Specific Multimodal Theranostics

W Xie, Y Gan, L Wang, Y Si, Q Li, T Song, P Wei, Z Wu… - Small, 2024 - Wiley Online Library
Copper‐based nanozymes exhibit excellent antitumor activity but are easily inactivated due
to the disturbance of proteins or other macromolecules with sulfhydryl. A tumor …

Imaging Fibrosis Progression in NASH with an Allysine-Reactive AIE Probe

Y Shan, N Sayed, KC Chong, HJ Ting, X Liu… - ACS Materials …, 2023 - ACS Publications
Nonalcoholic steatohepatitis (NASH) is prevalent in the global population, where up to one-
third of patients would further progress to developing fibrosis, cirrhosis, and hepatocellular …

Targeted platelet with hydrogen peroxide responsive behavior for non-alcoholic steatohepatitis detection

J Liu, X Liu, Y Shan, HJ Ting, X Yu, JW Wang, B Liu - Biomaterials, 2024 - Elsevier
The most common chronic liver illness, non-alcoholic fatty liver disease (NAFLD), refers to a
range of abnormalities of the liver with varying degrees of steatosis. When the clinical …

Enzyme-Catalyzed Molecular MR Imaging of Tumors

Z Wu, W Yang, B Zhang - TrAC Trends in Analytical Chemistry, 2024 - Elsevier
Enzymatic activity is a pivotal factor in cancer progression, necessitating the development of
in vivo imaging techniques for precise enzyme localization and quantification within tumors …

Integrin-Targeted Theranostic Nanoparticles for Clinical MRI-Traceable Treatment of Liver Fibrosis

Q Hu, Y Su, S Ma, P Wei, C He, D Yang… - … Applied Materials & …, 2024 - ACS Publications
Liver fibrosis is the critical stage in the development of chronic liver disease (CLD), from
simple injury to irreversible cirrhosis. Timely detection and intervention of liver fibrosis are …

A Two-Pronged Delivery Strategy Disrupting Positive Feedback Loop of Neutrophil Extracellular Traps for Metastasis Suppression

J Kong, Y Deng, Y Xu, P Zhang, L Li, Y Huang - ACS nano, 2024 - ACS Publications
Neutrophil extracellular traps (NETs) severely affect tumor metastasis through a self-
perpetuating feedback loop involving two key steps:(1) mitochondrial aerobic respiration …

A Contrast‐Enhanced Tri‐Modal MRI Technique for High‐Performance Hypoxia Imaging of Breast Cancer

Q Mao, M Gu, C Hong, H Wang, X Ruan, Z Liu, B Yuan… - Small, 2024 - Wiley Online Library
Personalized radiotherapy strategies enabled by the construction of hypoxia‐guided
biological target volumes (BTVs) can overcome hypoxia‐induced radioresistance by …

Iron oxide nanoclusters formed by acid-induced in situ calcium ion cross-linking for targeted magnetic resonance imaging of glioblastoma

R Xie, S Fu, G Zhu, H Ai, B Song, S Lui, G Li… - Chemical Engineering …, 2024 - Elsevier
Contrast agents (CAs) enhanced magnetic resonance imaging (MRI) are potential
candidates for the effective diagnosis of glioblastoma (GBM). However, the invasiveness …