Aminoglycoside antibiotics are employed clinically because of their potent bactericidal
activities, less bacterial resistance, post-antibiotic effects and low cost. However, drugs …

The aim of this study was focused on investigating the possible protective effect of NS
against GS-induced nephrotoxicity. Twenty four Wistar-albino rats were divided into four …

Acetaminophen (APAP) is a widely used analgesic and antipyretic drug, but at high dose it
leads to undesirable side effects, such as hepatotoxicity and nephrotoxicity. The present …

Introduction: Gentamicin sulphate nephrotoxicity seems to be attributed to the generation of
reactive oxygen species. Olive leaf extract (OLE) has been demonstrated to have antioxidant …

The present investigation reports the effect of rosmarinic acid (RA), an antioxidant on
gentamicin sulphate (GS)-induced renal oxidative damage in rats. Rosmarinic acid (RA) has …

Gentamicin (GM), one of the most commonly used aminoglycoside antibiotics, has been
used for treating pneumonia; however, the applicability of GM is limited by its bioavailability …

Background and aims. Gentamicin (GM) is still considered to be an important antibiotic
against life-threatening, gram-negative bacterial infections despite its known nephrotoxic …

Gentamicin, belonging to the aminoglycosides, possesses the greatest nephrotoxic effect of
all other antibiotics from this group. On the other hand, pioglitazone, which represents …

Salicylic acid (SA) and gentamicin (GM) loaded nanoparticles of chitosan (CS) cross-linked
with tripolyphosphate (TPP) were prepared and used to inhibit the ototoxicity of GM. The …

Clinical application of gentamicin (GM) is well known to be associated with the development
of acute kidney injury (AKI). This study was the first to investigate the possible protective …