The glycinergic inhibitory synapse

P Legendre - Cellular and Molecular Life Sciences CMLS, 2001 - Springer
Glycine is one of the most important inhibitory neurotransmitters in the spinal cord and the
brainstem, and glycinergic synapses have a well-established role in the regulation of …

Development of the locomotor network in zebrafish

P Drapeau, L Saint-Amant, RR Buss, M Chong… - Progress in …, 2002 - Elsevier
The zebrafish is a leading model for studies of vertebrate development and genetics. Its
embryonic motor behaviors are easy to assess (eg for mutagenic screens), the embryos …

Quantitative nanoscopy of inhibitory synapses: counting gephyrin molecules and receptor binding sites

CG Specht, I Izeddin, PC Rodriguez, M El Beheiry… - Neuron, 2013 - cell.com
The strength of synaptic transmission is controlled by the number and activity of
neurotransmitter receptors. However, little is known about absolute numbers and densities …

Neuronal and glial glycine transporters have different stoichiometries

MJ Roux, S Supplisson - Neuron, 2000 - cell.com
A neurotransmitter transporter can potentially mediate uptake or release of substrate, and its
stoichiometry is a key factor that controls the driving force and thus the neurotransmitter flux …

Characterisation of inhibitory and excitatory postsynaptic currents of the rat medial superior olive

AJ Smith, S Owens, ID Forsythe - The Journal of Physiology, 2000 - Wiley Online Library
1 The medial superior olive (MSO) is part of the binaural auditory pathway, receiving
excitatory projections from both cochlear nuclei and an inhibitory input from the ipsilateral …

Identification of a stereotypic molecular arrangement of endogenous glycine receptors at spinal cord synapses

SA Maynard, P Rostaing, N Schaefer, O Gemin… - Elife, 2021 - elifesciences.org
Precise quantitative information about the molecular architecture of synapses is essential to
understanding the functional specificity and downstream signaling processes at specific …

GABA and glycine co‐release optimizes functional inhibition in rat brainstem motoneurons in vitro

M Russier, IL Kopysova, N Ankri… - The Journal of …, 2002 - Wiley Online Library
Whole‐cell patch clamp recordings of miniature inhibitory postsynaptic currents (mIPSCs)
were obtained in identified abducens motoneurons (aMns) from young rats (P5‐P13). Three …

[HTML][HTML] Glycinergic transmission shaped by the corelease of GABA in a mammalian auditory synapse

T Lu, ME Rubio, LO Trussell - Neuron, 2008 - cell.com
The firing pattern of neurons is shaped by the convergence of excitation and inhibition, each
with finely tuned magnitude and duration. In an auditory brainstem nucleus, glycinergic …

Neurochemical development of brain stem nuclei involved in the control of respiration

MTT Wong-Riley, Q Liu - Respiratory physiology & neurobiology, 2005 - Elsevier
The first two postnatal weeks are the most dynamic in the development of brain stem
respiratory nuclei in the rat, the primary model for this review. Several neurochemicals …

Alpha subunit-dependent glycine receptor clustering and regulation of synaptic receptor numbers

A Patrizio, M Renner, R Pizzarelli, A Triller… - Scientific reports, 2017 - nature.com
Accumulation of glycine receptors at synapses requires the interaction between the beta
subunit of the receptor and the scaffold protein gephyrin. Here, we questioned whether …