▪ Abstract This review focuses on recent progress in our understanding of how mast cells
can contribute to the initiation, development, expression, and regulation of acquired immune …

The identification of novel helper T (Th) cell subsets, ie, IL-17-producing Th cells (Th17 cells)
and regulatory T cells (Treg cells), provided new insight into our understanding of the …

Observations of increased numbers of mast cells at sites of chronic inflammation have been
reported for over a hundred years. Light and electron microscopic evidence of mast cell …

Background Asthma is estimated to affect as many as 300 million people worldwide and its
incidence and prevalence are rapidly increasing throughout the world, especially in children …

Mast cells are best known as critical effector cells in anaphylaxis and other examples of IgE-
associated immediate hypersensitivity reactions. However, mast cells also can contribute to …

Human mast cells and basophils are conventionally considered primary effector cells of
bronchial asthma. There is now compelling evidence that these cells differ immunologically …

Mast cells are well known as versatile cells capable of releasing and producing a variety of
inflammatory mediators upon activation and are often found in close proximity of neurons. In …

Allergic eye diseases are complex inflammatory conditions of the conjunctiva with an
increasing prevalence and incidence. The diseases are often concomitant with other allergic …

Asthma is a common syndrome in children and adults. Despite the increasing prevalence
and socioeconomic burden, the underlying pathophysiology remains poorly defined in a …

Allergies are the result of an inappropriate reaction against innocuous environmental
proteins. The prevalence and severity of allergic diseases has increased dramatically during …