Benzimidazole based derivatives as anticancer agents: Structure activity relationship analysis for various targets

G Satija, B Sharma, A Madan, A Iqubal… - Journal of …, 2022 - Wiley Online Library
Benzimidazole, the benzo derivative of imidazole, is a class of bicyclic aromatic organic
compound consisting of six‐membered benzene ring fused to five‐membered imidazole at 4 …

The nano-based catalyst for the synthesis of benzimidazoles

RS Keri, V Adimule, P Kendrekar, BS Sasidhar - Topics in Catalysis, 2022 - Springer
The properties of benzimidazole and its derivatives have been studied over more than one
hundred years. The benzimidazole ring is an important pharmacophore in modern drug …

Spectroscopic characterization (IR, UV-Vis), and HOMO-LUMO, MEP, NLO, NBO analysis and the antifungal activity for 4-bromo-N-(2-nitrophenyl) benzamide; using …

SK Alghamdi, F Abbas, RK Hussein… - Journal of Molecular …, 2023 - Elsevier
In this study, the density functional theory was used to explore the spectral and electronic
properties of the title molecule, as well as a molecular docking technique to evaluate its …

Benzimidazole derivatives: A versatile scaffold for drug development against Helicobacter pylori‐related diseases

H Rostami, MH Haddadi - Fundamental & Clinical …, 2022 - Wiley Online Library
Helicobacter pylori (H. pylori) is a microaerophilic gastric pathogen and a major contributor
to chronic atrophic gastritis, peptic ulcer, and gastric malignancies. The increasing …

Design, Synthesis, Docking Study, and Antiproliferative Evaluation of Novel Schiff Base–Benzimidazole Hybrids with VEGFR-2 Inhibitory Activity

HM Abd El-Lateef, MAI Elbastawesy… - Molecules, 2023 - mdpi.com
A new series of Schiff–benzimidazole hybrids 3a–o has been designed and synthesized.
The structure of the target compounds was proved by different spectroscopic and elemental …

Dual Photochemistry of Benzimidazole

JPL Roque, MTS Rosado, R Fausto… - The Journal of Organic …, 2023 - ACS Publications
Monomers of benzimidazole trapped in an argon matrix at 15 K were characterized by
vibrational spectroscopy and identified as 1 H-tautomers exclusively. The photochemistry of …

Imidazobenzimidazole fused azacalix [4] arenes: Synthesis, structure, and Zn2+-selective colorimetric-fluorometric sensor

YT Huang, M Xue, Y Yang - Chinese Chemical Letters, 2023 - Elsevier
Abstract Tetra (amino) azacalix [4] arene skeleton was functionalized at the bridging NH
sites using various aromatic aldehydes via formation of imidazobenzimidazole fused …

Chalcones as Anti-Infective Agents for Effective Management of Tuberculosis

S Mishra, P Jana - Polycyclic Aromatic Compounds, 2023 - Taylor & Francis
After the pandemic COVID-19, global health agencies remind us that tuberculosis is the
deadliest infectious disease worldwide. As per WHO reports, approximately ten million …

Exploring the Synthetic and Antioxidant Potential of 1,2‐Disubstituted Benzimidazoles using [Et3NH][HSO4] Ionic Liquid Catalyst

N Sahiba, P Teli, P Meena… - Chemistry & Biodiversity, 2023 - Wiley Online Library
Abstract An [Et3NH][HSO4] ionic‐liquid catalyzed, intermolecular C− N bond formation for 1,
2‐disubstituted benzimidazole synthesis was achieved by the reaction of OPD and …

Exploring antimalarial potential: Conjugating organometallic moieties with organic fragments for enhanced efficacy

NAZ Norazmi, NH Mukhtar, L Ravindar, AS Saaidin… - Bioorganic …, 2024 - Elsevier
In the search for novel ligands with efficacy against various diseases, particularly parasitic
diseases, molecular hybridization of organometallic units into biologically active scaffolds …