This work reports on the proof-of-concept of a photoelectrochemical (PEC) biosensor with a
horseradish peroxidase-single stranded DNA-encoded magnetic bead (MB-ssDNA-HRP) …

Mature microRNAs (miRNAs) in extracellular vesicles (EVs) are involved in different stages
of cancer progression, yet it remains challenging to precisely detect mature miRNAs in EVs …

As important post‐transcriptional regulators, microRNAs (miRNAs) play irreplaceable roles
in diverse cellular functions. Dysregulated miRNA expression is implicated in various …

The accurate, rapid, and sensitive identification of cancer cells in complex physiological
environments is significant in biological studies, personalized medicine, and biomedical …

Nucleic acids are essential biomarkers in molecular diagnostics. The CRISPR/Cas system
has been widely used for nucleic acid detection. Moreover, canonical CRISPR/Cas12a …

Lung cancer is the leading cause of cancer-related death around the world. The circulating
tumor DNA (ctDNA) of EGFR L858R in plasma is crucial for development, targeted drug …

Meat adulteration can cause consumer fraud, food allergies, and religious issues. Rapid and
sensitive detection methods are urgently demanded to supervise meat authenticity. Herein …

While three-dimensional (3D) DNA walking amplifiers hold considerable promise in the
construction of advanced DNA-based fluorescent biosensors for bioimaging, they encounter …

DNA nanosheets (DNSs) have been utilized effectively as a fluorescence anisotropy (FA)
amplifier for biosensing. But, their sensitivity needs to be further improved. Herein, CRISPR …

Nucleic acid amplification strategies have successfully dominated ultrasensitive bioassays,
but they sometimes bring high time-consumption, multi-step operation, increased …