Oxalate homeostasis is maintained through a delicate balance between endogenous
sources, exogenous supply and excretion from the body. Novel studies have shed light on …

Hyperoxaluria results from either inherited disorders of glyoxylate metabolism leading to
hepatic oxalate overproduction (primary hyperoxaluria), or increased intestinal oxalate …

Obesity increases the risk of several diseases, including kidney stone disease (KSD). The
study aimed to explore the relationship between KSD and various obesity-related indices. A …

Oxalate is both a plant-derived molecule and a terminal toxic metabolite with no known
physiological function in humans. It is predominantly eliminated by the kidneys through …

Kidney stone disease (KSD) is one of the earliest medical diseases known, but the
mechanism of its formation and metabolic changes remain unclear. The formation of kidney …

The prevalence of obesity is rising and places this cohort at risk for developing kidney
stones. Some of the pathophysiologic responses that link obesity and kidney stone formation …

Objectives: Diabetes mellitus is a chronic disease requiring lifelong medical attention. With
hundreds of millions suffering worldwide and a rapidly rising incidence, diabetes mellitus …

Background Kidney stone disease affects approximately 10% of individuals in their lifetime
and is frequently recurrent. The disease is linked to obesity, but the mechanisms mediating …

Oxalate is an ionic form of a potentially toxic oxalic acid that is formed in the human body
from a combination of food sources and their absorption in the gastrointestinal tract …

Kidney stones constitute a disease of the urinary system of high incidence that has only a
few available stone dissolving drugs as treatment options. The mechanism of calcium …