Electrochemical biosensors in exosome analysis; a short journey to the present and future trends in early-stage evaluation of cancers

E Dezhakam, B Khalilzadeh, M Mahdipour… - Biosensors and …, 2023 - Elsevier
The tumor microenvironment consists of a multiplicity of cells such as cancer cells,
fibroblasts, endothelial cells, and immune cells within the specific parenchyma. It has been …

Protein cargo in extracellular vesicles as the key mediator in the progression of cancer

K Hánělová, M Raudenská, M Masařík… - Cell Communication and …, 2024 - Springer
Exosomes are small vesicles of endosomal origin that are released by almost all cell types,
even those that are pathologically altered. Exosomes widely participate in cell-to-cell …

Analysis of microRNAs in exosomes of breast cancer patients in search of molecular prognostic factors in brain metastases

CJ Curtaz, L Reifschläger, L Strähle… - International Journal of …, 2022 - mdpi.com
Brain metastases are the most severe tumorous spread during breast cancer disease. They
are associated with a limited quality of life and a very poor overall survival. A subtype of …

Characterization of exosome-related gene risk model to evaluate the tumor immune microenvironment and predict prognosis in triple-negative breast cancer

P Qiu, Q Guo, Q Yao, J Chen, J Lin - Frontiers in immunology, 2021 - frontiersin.org
Background As a kind of small membrane vesicles, exosomes are secreted by most cell
types from multivesicular endosomes, including tumor cells. The relationship between …

[HTML][HTML] Extracellular vesicle-mediated transport: Reprogramming a tumor microenvironment conducive with breast cancer progression and metastasis

D Brena, MB Huang, V Bond - Translational oncology, 2022 - Elsevier
Breast cancer metastatic progression to critical secondary sites is the second leading cause
of cancer-related mortality in women. While existing therapies are highly effective in …

Enigmatic role of exosomes in breast cancer progression and therapy

P Famta, S Shah, DK Khatri, SK Guru, SB Singh… - Life Sciences, 2022 - Elsevier
Breast cancer (BC) is reported to be the leading cause of mortality in females worldwide. At
the beginning of the year 2021, about 7.8 million women were diagnosed with BC in past 5 …

The application of exosomes in the treatment of triple-negative breast cancer

JW Weaver, J Zhang, J Rojas, PR Musich… - Frontiers in Molecular …, 2022 - frontiersin.org
Triple-negative breast cancer (TNBC) is a heterogeneous and invasive breast cancer (BC)
subtype that is estrogen receptor-negative, progesterone receptor-negative, and human …

Exosomes: a forthcoming era of breast cancer therapeutics

B Bondhopadhyay, S Sisodiya, FA Alzahrani… - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer prevalence is a major challenge worldwide due to the lack
of early diagnostics and treatment modalities. In this era of technological advancements …

Fast quantification of extracellular vesicles levels in early breast cancer patients by Single Molecule Detection Array (SiMoA)

C Morasso, A Ricciardi, D Sproviero, M Truffi… - Breast Cancer Research …, 2022 - Springer
Purpose Preliminary reports suggest that extracellular vesicles (EVs) might be a promising
biomarker for breast cancer (BC). However, the quantification of plasmatic levels of EVs is a …

Clinical relevance of exosome-derived microRNAs in Ovarian Cancer: Looking for new tumor biological fingerprints

D Fanale, LR Corsini, M Bono, U Randazzo… - Critical Reviews in …, 2023 - Elsevier
Specific tumor-derived extracellular vesicles, called exosomes, are considered as potential
key players in cross-talk between immune system and tumor microenvironment in several …