Potential therapeutics using tumor-secreted lactate in nonsmall cell lung cancer

ZX Liao, IM Kempson, CC Hsieh, SJ Tseng… - Drug Discovery …, 2021 - Elsevier
Targeted-therapy failure in treating nonsmall cell lung cancer (NSCLC) frequently occurs
because of the emergence of drug resistance and genetic mutations. The same mutations …

The relationship between LDH and GLIM criteria for cancer cachexia: Systematic Review and Meta-Analysis.

J Thompson, J McGovern, C Roxburgh… - Critical Reviews in …, 2024 - Elsevier
Introduction Cancer cachexia is a clinical condition characterized by recognizable “sickness
behaviors” accompanied by loss of lean body tissue. The Global Leadership on Malnutrition …

About the associations of vitamin D deficiency and biomarkers of systemic inflammatory response with all-cause and cause-specific mortality in a general population …

S Sha, T Gwenzi, LJ Chen, H Brenner… - European journal of …, 2023 - Springer
It is unknown whether the well-known association between vitamin D deficiency and
mortality could be explained by the immune system modulating effects of vitamin D, which …

Additional diagnostic value of the monocyte to red blood cell count ratio and the product of lymphocyte count and albumin concentration in lung cancer management

XX Chen, ST Zhao, XM Yang, SC He… - Oncology …, 2023 - spandidos-publications.com
The present study aimed to evaluate the potential of the monocyte to red blood cell count
ratio (MRR), the neutrophil to red blood cell count ratio (NRR), the lymphocyte to red blood …

Brain metastasis, EGFR mutation subtype and generation of EGFR-TKI jointly influence the treatment outcome of patient with EGFR-mutant NSCLC

JS Ju, ACC Huang, PH Tung, CH Huang, TH Chiu… - Scientific Reports, 2023 - nature.com
Non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) mutation
is brain metastasis (BM)-prone. We determined the impact of this hallmark, along with EGFR …

Associations between peripheral whole blood cell counts derived indexes and cancer prognosis: An umbrella review of meta-analyses of cohort studies

YY Zhang, FH Liu, YL Wang, JX Liu, L Wu, Y Qin… - Critical Reviews in …, 2024 - Elsevier
Meta-analyses have reported conflicting data on the whole blood cell count (WBCC) derived
indexes (neutrophil-to-lymphocyte ratio [NLR], platelet-to-lymphocyte ratio [PLR], and …

Absolute lymphocyte count as an independent prognostic factor in metastatic breast cancer: A retrospective study

A Sawa, H Bando, R Kamohara, N Takeuchi… - Oncology, 2022 - karger.com
Introduction: Recently, absolute lymphocyte count (ALC) and neutrophil-to-lymphocyte ratio
(NLR) have been reported to be prognostic and/or predictive factors in breast cancer …

Prognostic values of inflammatory indexes in bevacizumab-treated patients with advanced non-small-cell lung cancer

J Yang, M Deng, M Bi, Y Wang, X Qiao… - Future Science …, 2022 - Taylor & Francis
Purpose: Inflammatory indexes, including neutrophil-to-lymphocyte ratio (NLR), platelet-to-
lymphocyte ratio (PLR), systemic immune-inflammation index (SII) and lymphocyte-to …

Systemic inflammation index and tumor glycolytic heterogeneity help risk stratify patients with advanced epidermal growth factor receptor-mutated lung …

KH Lue, CH Huang, TC Hsieh, SH Liu, YF Wu… - Cancers, 2022 - mdpi.com
Simple Summary Patients with advanced epidermal growth factor receptor (EGFR)-mutated
lung adenocarcinoma have been known to respond to first-line tyrosine kinase inhibitor (TKI) …

Rare Driver Mutations in Advanced, Oncogene-Addicted Non-Small Cell Lung Cancer: A North Italian, Real-World, Registry Experience

K Andrikou, P Ulivi, E Petracci, I Azzali, F Bertolini… - Diagnostics, 2024 - mdpi.com
The real-world, retrospective, NEROnE registry investigated the impact of next-generation
sequencing (NGS) in advanced non-small-cell lung cancer (NSCLC) patients (pts) at three …