Nephroprotective role of bromelain against oxidative injury induced by aluminium in rats

FM El-Demerdash, HH Baghdadi, NF Ghanem… - Environmental …, 2020 - Elsevier
The present study was designed to investigate the nephroprotective effect of bromelain
against oxidative stress stimulated by aluminium chloride in rats. Rats were grouped as …

The ameliorative effect of bromelain on STZ-induced type 1 diabetes in rats through Oxi-LDL/LPA/LPAR1 pathway

NFA El-Magd, NM Ramadan, SM Eraky - Life Sciences, 2021 - Elsevier
Aims Diabetes, a serious worldwide problem, is modulated via inflammation and oxidative
stress. Bromelain, a natural compound, recently attracts interest due to its anti-inflammatory …

Bromelain ameliorates D-galactosamine-induced acute liver injury: role of SIRT1/LKB1/AMPK, GSK3β/Nrf2 and NF-κB p65/TNF-α/caspase-8,-9 signalling pathways

MA Didamoony, AM Atwa… - Journal of Pharmacy …, 2022 - academic.oup.com
Objectives The present research focused on estimating, for the first time, the potential
protective effects of bromelain against D-galactosamine-induced acute liver injury in rats as …

Bromelain from Ananas comosus stem attenuates oxidative toxicity and testicular dysfunction caused by aluminum in rats

AB Jebur, FM El-Demerdash, W Kang - … of Trace Elements in Medicine and …, 2020 - Elsevier
BACKGROUND Aluminum (Al) has been reported to induce testicular injury via oxidative
stress. Ananas comosus stem extract is an inexpensive byproduct waste rich in bromelain …

Bacoside A and bromelain relieve dichlorvos induced changes in oxidative responses in mice serum

S Agarwal, B Chaudhary, R Bist - Chemico-biological interactions, 2016 - Elsevier
Reactive oxygen species (ROS) may be involved in the pathogenesis of serum induced by
dichlorvos. Therefore, the rationale of present research was to evaluate the ameliorative …

Bromelain reduces the non‐alcoholic fatty liver disease and periodontal damages caused by ligature‐induced periodontitis

EHP Alves, AS Carvalho, FRP Silva… - Oral …, 2020 - Wiley Online Library
Objective The objective of this research was to evaluate the effects of bromelain (derived
from Ananas comosus) upon periodontitis in rats. Materials and Methods Twenty‐four rats …

Dietary pineapple peel ethanolic extract alleviates crowding stress in Labeo rohita fingerlings with enhancement of growth performance and IGF-1 expression, physio …

S Bhattacharya, P Sardar, NP Sahu, N Shamna… - Animal Feed Science …, 2024 - Elsevier
Crowding stress in intensified aquaculture system reduces growth of fish. However, dietary
pineapple peel ethanolic extract derived bioactive compounds are expected to minimize …

Bromelain mitigates liver fibrosis via targeting hepatic stellate cells in vitro and in vivo

AA Sayed, AM Soliman, M Marzouk, FF Mohammed… - Tissue and Cell, 2023 - Elsevier
Various therapeutic approaches are conducted for regression of liver fibrosis and prevent
possible further carcinogenic transformation. This study was aimed to assess the …

Bromelain Modulates Liver Injury, Hematological, Molecular, and Biochemical Perturbations Induced by Aluminum via Oxidative Stress Inhibition

FM El-Demerdash, DM Hussien… - BioMed Research …, 2022 - Wiley Online Library
Aluminum (Al) is an important factor in the environment as it is used in agriculture and
several industries leading to hazardous effects via oxidative stress. Bromelain is a cheap …

Role of caftaric acid in lead-associated nephrotoxicity in rats via antidiuretic, antioxidant and anti-apoptotic activities

KMM Koriem, MS Arbid - Journal of Complementary and Integrative …, 2018 - degruyter.com
Background Lead is a toxic metal that is widely distributed in the environment where caftaric
acid (CA) is the ester form of caffeic acid where CA is the major dietary polyphenol present …