[HTML][HTML] Determinants and outcomes of mitochondrial dynamics

R Quintana-Cabrera, L Scorrano - Molecular Cell, 2023 - cell.com
Mitochondria are not only central organelles in metabolism and energy conversion but are
also platforms for cellular signaling cascades. Classically, the shape and ultrastructure of …

[HTML][HTML] Mitochondrial fusion and fission: The fine-tune balance for cellular homeostasis

M Adebayo, S Singh, AP Singh… - FASEB journal: official …, 2021 - ncbi.nlm.nih.gov
Mitochondria are highly dynamic, maternally inherited cytoplasmic organelles, which fulfill
cellular energy demand through the oxidative phosphorylation system. Besides, they play an …

The cell biology of mitochondrial membrane dynamics

M Giacomello, A Pyakurel, C Glytsou… - Nature reviews Molecular …, 2020 - nature.com
Owing to their ability to efficiently generate ATP required to sustain normal cell function,
mitochondria are often considered the 'powerhouses of the cell'. However, our …

The role of mitochondrial fission in cardiovascular health and disease

JM Quiles, ÅB Gustafsson - Nature Reviews Cardiology, 2022 - nature.com
Mitochondria are organelles involved in the regulation of various important cellular
processes, ranging from ATP generation to immune activation. A healthy mitochondrial …

Function and regulation of the divisome for mitochondrial fission

F Kraus, K Roy, TJ Pucadyil, MT Ryan - Nature, 2021 - nature.com
Mitochondria form dynamic networks in the cell that are balanced by the flux of iterative
fusion and fission events of the organelles. It is now appreciated that mitochondrial fission …

Molecular mechanisms of mitochondrial dynamics

LC Tábara, M Segawa, J Prudent - Nature Reviews Molecular Cell …, 2024 - nature.com
Mitochondria not only synthesize energy required for cellular functions but are also involved
in numerous cellular pathways including apoptosis, calcium homoeostasis, inflammation …

Mitochondrial quality control in kidney injury and repair

C Tang, J Cai, XM Yin, JM Weinberg… - Nature Reviews …, 2021 - nature.com
Mitochondria are essential for the activity, function and viability of eukaryotic cells and
mitochondrial dysfunction is involved in the pathogenesis of acute kidney injury (AKI) and …

Mitochondrial dynamics: overview of molecular mechanisms

L Tilokani, S Nagashima, V Paupe… - Essays in …, 2018 - portlandpress.com
Mitochondria are highly dynamic organelles undergoing coordinated cycles of fission and
fusion, referred as 'mitochondrial dynamics', in order to maintain their shape, distribution and …

ER as master regulator of membrane trafficking and organelle function

EM Wenzel, LA Elfmark, H Stenmark… - Journal of cell biology, 2022 - rupress.org
The endoplasmic reticulum (ER), which occupies a large portion of the cytoplasm, is the
cell's main site for the biosynthesis of lipids and carbohydrate conjugates, and it is essential …

Multi-color live-cell STED nanoscopy of mitochondria with a gentle inner membrane stain

T Liu, T Stephan, P Chen… - Proceedings of the …, 2022 - National Acad Sciences
Capturing mitochondria's intricate and dynamic structure poses a daunting challenge for
optical nanoscopy. Different labeling strategies have been demonstrated for live-cell …