Glioblastoma Multiforme (GBM) is a grade IV primary malignant brain tumour, which is highly
infiltrative and exhibits a poor prognosis which results in high mortality. Low solubility and …

Black seeds, sometimes called black cumin, are obtained from the spicy medicinal herb
Nigella sativa that is native to a broad region encompassing the eastern Mediterranean …

Objective (s): We aimed to investigate the levels of transient receptor potential melastatin
(TRPM) gene expression, and the antioxidant and histopathologic effect of thymoquinone …

Thymoquinone (TQ) is the main biologically active substance of Nigella sativa (black seeds).
It has anti-cancer, anti-inflammatory, anti-diabetic, anti-oxidative and anti-nociceptive …

Neurodegenerative diseases are characterized by slowly progressing neuronal cell death.
Conventional drug treatment strategies often fail because of poor solubility, low …

Neurodegenerative diseases are characterized by slowly progressive neuronal death.
Conventional treatment strategies often fail due to poor solubility, lower bioavailability, and …

Introduction: Dependence and withdrawal syndrome caused by opioids are the most
important and unambiguous factors in the clinical use of narcotic painkillers. Some evidence …

Aim: Thymoquinone (TQ) is derived from Nigella Sativa (NS) which is a traditional medicinal
plant used as a spice, and medication in traditional medicine. This study aims to investigate …

Abstract Ischemia/Reperfusion (I/R) injury is surgery and clinically important problem. It was
showed that Ca+ 2 concentration increases into cell with I/R injury. TRPM channels have a …