The lateral habenula (LH b) is an epithalamic region with a crucial role in the regulation of
midbrain monoaminergic systems. Over the past few years a renewed interest in the LH b …

The habenula is an epithalamic structure located at the center of the dorsal diencephalic
conduction system, a pathway involved in linking forebrain to midbrain regions. Composed …

The cytology and connections of the lateral habenula (LHb) are reviewed. The habenula is
first introduced, after which the cytology of the LHb is discussed mainly with reference to cell …

Tobacco smoking is a serious health problem worldwide and a leading cause of mortality.
Nicotine, the addictive component of tobacco, affects a range of emotional responses …

Dopamine plays a key role in the cellular and behavioral responses to drugs of abuse, but
the implication of metabotropic regulatory input to dopaminergic neurons on acute drug …

Nicotine is one of the most addictive drugs of abuse. Tobacco smoking is a major cause of
many health problems, and is the first preventable cause of death worldwide. Several …

Although potent effects of psychoactive drugs on circadian rhythms were first described over
30 years ago, research into the reciprocal relationship between the reward system and the …

The lateral habenula (LHb) is a brain structure receiving inputs from limbic forebrain areas
and innervating major midbrain monoaminergic nuclei. Evidence indicates LHb involvement …

Despite extensive research in recent decades, knowledge of the pathophysiology of
depression in neural circuits remains limited. Recently, the lateral habenula (LHb) has been …

Sensitivity to rewarding and reinforcing drug effects has a critical role in initial use, but the
role of initial aversive drug effects has received less attention. Methamphetamine effects on …