During the past decade enormous advances have been made in our understanding of the
basic molecular machinery that is involved in the development of neuronal polarity. Far from …

After they are born and differentiate, neurons break their previous symmetry, dramatically
change their shape, and establish two structurally and functionally distinct compartments …

Neurons are among the most highly polarized cell types in the body, and the polarization of
axon and dendrites underlies the ability of neurons to integrate and transmit information in …

Extension of neurites from a cell body is essential to form a functional nervous system;
however, the mechanisms underlying neuritogenesis are poorly understood. Ena/VASP …

Primary cilia are displayed during the G0/G1 phase of many cell types. Cilia are resorbed as
cells prepare to re-enter the cell cycle, but the causal and molecular link between these two …

Mammalian cortical development involves neuronal migration and neuritogenesis; this latter
process forms the structural precursors to axons and dendrites. Elucidating the pathways …

Disrupted-In-Schizophrenia 1 (DISC1) is a candidate gene for susceptibility to
schizophrenia. DISC1 is reported to interact with NudE-like (NUDEL), which forms a …

As motile organelles and sensors, cilia play pivotal roles in cell physiology, development
and organ homeostasis. Ciliary defects are associated with a class of cilia-related diseases …

Recent studies of the primary cilium have begun to provide further insights into ciliary
ultrastructure, with an emerging picture of complex compartmentalization and molecular …

Important progress has been made during the past decade in the identification of molecular
motors required in the distribution of early and late endosomes and the proper trafficking …