Cromolyn Sodium differentially regulates human mast cell and mouse leukocyte responses to control allergic inflammation

PG Puzzovio, TR Brüggemann, H Pahima… - Pharmacological …, 2022 - Elsevier
Abstract Background Cromolyn Sodium (CS) has been used in the past as an anti-allergy
drug owing to its mast cell (MC) stabilizing properties that impair histamine release …

High expression of CD300A predicts poor survival in acute myeloid leukemia

H Zhuang, F Li, T Si, R Pei, M Yu, D Chen, PP Ye… - Acta …, 2023 - karger.com
Introduction: Recent studies have suggested that CD300A was an oncogene in acute
myeloid leukemia (AML) development. However, the clinical relevance and biological …

CD300a regulates mouse macrophage functionality in allergic inflammation

PG Puzzovio, BD Levy, F Levi-Schaffer - International archives of allergy …, 2023 - karger.com
Background: CD300a is an inhibitory receptor (IR) expressed on several leukocytes,
including mast cells (MCs) and macrophages (MΦ), important cells in allergic inflammation …

Neutrophil-related genes predict prognosis and contribute to immunosuppression in acute myeloid leukemia

D Zhang, Y Li, T Liu, X Liu, J Zhang - 2024 - researchsquare.com
Neutrophils, the predominant myeloid cells in human blood, have been implicated as pivotal
contributors to cancer development. However, the relationship between neutrophils and …

The inhibitory receptor CD300a functions as an immune checkpoint in a mouse model of breast cancer

M Ben-Zimra, S Niazov, FR Alekberly, F Levi-Schaffere - 2024 - researchsquare.com
Breast cancer (BC) is the second most common cancer type in women and still a major
cause of death. In the USA it is estimated that 42,250 women will die in 2024 from BC. Over …