Gram-negative neonatal sepsis in low-and lower-middle-income countries and WHO empirical antibiotic recommendations: A systematic review and meta-analysis
Background Neonatal sepsis is a significant global health issue associated with marked
regional disparities in mortality. Antimicrobial resistance (AMR) is a growing concern in …
regional disparities in mortality. Antimicrobial resistance (AMR) is a growing concern in …
Genetic Determinants of Resistance among ESBL‐Producing Enterobacteriaceae in Community and Hospital Settings in East, Central, and Southern Africa: A …
OG Onduru, RS Mkakosya, S Aboud… - Canadian Journal of …, 2021 - Wiley Online Library
Background. The world prevalence of community and hospital‐acquired extended‐spectrum
β-lactamase (ESBL)‐producing Enterobacteriaceae is increasing tremendously. Bacteria …
β-lactamase (ESBL)‐producing Enterobacteriaceae is increasing tremendously. Bacteria …
Characterization of antimicrobial-resistant Gram-negative bacteria that cause neonatal sepsis in seven low-and middle-income countries
Antimicrobial resistance in neonatal sepsis is rising, yet mechanisms of resistance that often
spread between species via mobile genetic elements, ultimately limiting treatments in low …
spread between species via mobile genetic elements, ultimately limiting treatments in low …
Variation of effect estimates in the analysis of mortality and length of hospital stay in patients with infections caused by bacteria-producing extended-spectrum beta …
Objective To assess the variation of effect estimates in the analysis of mortality and length of
stay (LOS) in patients with infections caused by extended-spectrum beta-lactamase (ESBL) …
stay (LOS) in patients with infections caused by extended-spectrum beta-lactamase (ESBL) …
Neonatal sepsis at Mulago national referral hospital in Uganda: Etiology, antimicrobial resistance, associated factors and case fatality risk
J Tumuhamye, H Sommerfelt, F Bwanga, G Ndeezi… - PloS one, 2020 - journals.plos.org
Background Sepsis is the third most common cause of death among neonates, with about
225,000 newborns dying every year globally. Data concerning the microbial etiology of …
225,000 newborns dying every year globally. Data concerning the microbial etiology of …
Multicenter genomic analysis of carbapenem-resistant Klebsiella pneumoniae from bacteremia in China
AV Cienfuegos-Gallet, Y Zhou, W Ai… - Microbiology …, 2022 - Am Soc Microbiol
Klebsiella pneumoniae is one of the most common Gram-negative bacilli isolated from
bloodstream infections worldwide, and recently an increased rate of carbapenem resistance …
bloodstream infections worldwide, and recently an increased rate of carbapenem resistance …
Prevalence and outcome of bloodstream infections due to third-generation cephalosporin-resistant Enterobacteriaceae in sub-Saharan Africa: a systematic review
R Lester, P Musicha, N Van Ginneken… - Journal of …, 2020 - academic.oup.com
Background The prevalence of bacterial bloodstream infections (BSIs) in sub-Saharan Africa
(sSA) is high and antimicrobial resistance is likely to increase mortality from these infections …
(sSA) is high and antimicrobial resistance is likely to increase mortality from these infections …
Existence of Multiple ESBL Genes among Phenotypically Confirmed ESBL Producing Klebsiella pneumoniae and Escherichia coli Concurrently Isolated from …
The proportions and similarities of extended-spectrum β-lactamase (ESBL) producing K.
pneumoniae (ESBL-KP) and E. coli (ESBL-EC) carrying multiple ESBL genes is poorly …
pneumoniae (ESBL-KP) and E. coli (ESBL-EC) carrying multiple ESBL genes is poorly …
OXA-181-like carbapenemases in Klebsiella pneumoniae ST14, ST15, ST23, ST48, and ST231 from septicemic neonates: coexistence with NDM-5, resistome …
Studies on the epidemiology and genomes of isolates harboring OXA-48-like genes in
septicemic neonates are rare. Here, isolates producing these carbapenemases which …
septicemic neonates are rare. Here, isolates producing these carbapenemases which …
Genetic diversity and risk factors for the transmission of antimicrobial resistance across human, animals and environmental compartments in East Africa: a review
Background The emergence and spread of antimicrobial resistance (AMR) present a
challenge to disease control in East Africa. Resistance to beta-lactams, which are by far the …
challenge to disease control in East Africa. Resistance to beta-lactams, which are by far the …