Systematic exploration of Escherichia coli phage–host interactions with the BASEL phage collection
Bacteriophages, the viruses infecting bacteria, hold great potential for the treatment of
multidrug-resistant bacterial infections and other applications due to their unparalleled …
multidrug-resistant bacterial infections and other applications due to their unparalleled …
The base excision repair process: comparison between higher and lower eukaryotes
The base excision repair (BER) pathway is essential for maintaining the stability of DNA in
all organisms and defects in this process are associated with life-threatening diseases. It is …
all organisms and defects in this process are associated with life-threatening diseases. It is …
Evaluation of DNA double-strand break repair capacity in human cells: Critical overview of current functional methods
X Tatin, G Muggiolu, S Sauvaigo, J Breton - Mutation Research/Reviews in …, 2021 - Elsevier
DNA double-strand breaks (DSBs) are highly deleterious lesions, responsible for
mutagenesis, chromosomal translocation or cell death. DSB repair (DSBR) is therefore a …
mutagenesis, chromosomal translocation or cell death. DSB repair (DSBR) is therefore a …
Mismatch discrimination and sequence bias during end-joining by DNA ligases
DNA ligases, critical enzymes for in vivo genome maintenance and modern molecular
biology, catalyze the joining of adjacent 3′-OH and 5′-phosphorylated ends in DNA. To …
biology, catalyze the joining of adjacent 3′-OH and 5′-phosphorylated ends in DNA. To …
Recognition of an unnatural base pair by tool enzymes from bacteriophages and its application in the enzymatic preparation of DNA with an expanded genetic …
J Bai, J Zou, Y Cao, Y Du, T Chen - ACS Synthetic Biology, 2023 - ACS Publications
Unnatural base pairs (UBPs) have been developed to expand the genetic alphabet in vitro
and in vivo. UBP dNaM-dTPT3 and its analogues have been successfully used to construct …
and in vivo. UBP dNaM-dTPT3 and its analogues have been successfully used to construct …
A single-molecule sequencing assay for the comprehensive profiling of T4 DNA ligase fidelity and bias during DNA end-joining
DNA ligases are key enzymes in molecular and synthetic biology that catalyze the joining of
breaks in duplex DNA and the end-joining of DNA fragments. Ligation fidelity (discrimination …
breaks in duplex DNA and the end-joining of DNA fragments. Ligation fidelity (discrimination …
Human DNA ligases I and III have stand-alone end-joining capability, but differ in ligation efficiency and specificity
JR McNally, AM Ames, SJ Admiraal… - Nucleic Acids …, 2023 - academic.oup.com
Double-strand DNA breaks (DSBs) are toxic to cells, and improper repair can cause
chromosomal abnormalities that initiate and drive cancer progression. DNA ligases III and IV …
chromosomal abnormalities that initiate and drive cancer progression. DNA ligases III and IV …
Characterisation and engineering of a thermophilic RNA ligase from Palaeococcus pacificus
M Rousseau, T Oulavallickal, A Williamson… - Nucleic Acids …, 2024 - academic.oup.com
RNA ligases are important enzymes in molecular biology and are highly useful for the
manipulation and analysis of nucleic acids, including adapter ligation in next-generation …
manipulation and analysis of nucleic acids, including adapter ligation in next-generation …
Profiling DNA Ligase Substrate Specificity with a Pacific Biosciences Single‐Molecule Real‐Time Sequencing Assay
AT Duckworth, K Bilotti, V Potapov… - Current …, 2023 - Wiley Online Library
DNA ligases catalyze the joining of breaks in nucleic acid backbones and are essential
enzymes for in vivo genome replication and repair across all domains of life. These enzymes …
enzymes for in vivo genome replication and repair across all domains of life. These enzymes …
Reconfiguration of DNA nanostructures induced by enzymatic ligation treatment
Enzymatic ligation is a popular method in DNA nanotechnology for structural enforcement.
When employed as stability switch for chosen components, ligation can be applied to induce …
When employed as stability switch for chosen components, ligation can be applied to induce …