Escherichia coli-derived virus-like particles in vaccine development
Recombinant virus-like particle-based vaccines are composed of viral structural proteins
and mimic authentic native viruses but are devoid of viral genetic materials. They are the …
and mimic authentic native viruses but are devoid of viral genetic materials. They are the …
The development of a recombinant hepatitis E vaccine HEV 239
SW Li, Q Zhao, T Wu, S Chen, J Zhang… - Human vaccines & …, 2015 - Taylor & Francis
Hepatitis E virus (HEV) infection is one of the main causes of acute hepatitis worldwide. A
recombinant hepatitis E vaccine, HEV 239, has been licensed in China for immunizing …
recombinant hepatitis E vaccine, HEV 239, has been licensed in China for immunizing …
Public health risks associated with hepatitis E virus (HEV) as a food‐borne pathogen
EFSA Panel on Biological Hazards (BIOHAZ)… - Efsa …, 2017 - Wiley Online Library
Hepatitis E virus (HEV) is an important infection in humans in EU/EEA countries, and over
the last 10 years more than 21,000 acute clinical cases with 28 fatalities have been notified …
the last 10 years more than 21,000 acute clinical cases with 28 fatalities have been notified …
Life cycle and morphogenesis of the hepatitis E virus
K Himmelsbach, D Bender, E Hildt - Emerging microbes & …, 2018 - Taylor & Francis
Hepatitis E virus (HEV) is transmitted primarily via contaminated water and food by the fecal
oral route and causes epidemics in developing countries. In industrialized countries …
oral route and causes epidemics in developing countries. In industrialized countries …
Robust manufacturing and comprehensive characterization of recombinant hepatitis E virus-like particles in Hecolin®
The hepatitis E virus (HEV) vaccine, Hecolin®, was licensed in China for the prevention of
HEV infection and HEV-related diseases with demonstrated safety and efficacy [1],[2]. The …
HEV infection and HEV-related diseases with demonstrated safety and efficacy [1],[2]. The …
[HTML][HTML] Hepatitis E: A disease of reemerging importance
S Sridhar, SKP Lau, PCY Woo - Journal of the Formosan Medical …, 2015 - Elsevier
Hepatitis E virus (HEV) is the most common cause of acute viral hepatitis worldwide.
Originally considered to be restricted to humans, it is now clear that HEV and HEV-like …
Originally considered to be restricted to humans, it is now clear that HEV and HEV-like …
Hepatitis E virus as an emerging zoonotic pathogen
WJ Park, BJ Park, HS Ahn, JB Lee… - Journal of …, 2016 - synapse.koreamed.org
Hepatitis E outbreaks are a serious public health concern in developing countries. The
disease causes acute infections, primarily in young adults. The mortality rate is …
disease causes acute infections, primarily in young adults. The mortality rate is …
Cell binding tropism of rat hepatitis E virus is a pivotal determinant of its zoonotic transmission to humans
H Guo, J Xu, J Situ, C Li, X Wang, Y Hou… - Proceedings of the …, 2024 - pnas.org
Classically, all hepatitis E virus (HEV) variants causing human infection belong to the genus
Paslahepevirus (HEV-A). However, the increasing cases of rat HEV infection in humans …
Paslahepevirus (HEV-A). However, the increasing cases of rat HEV infection in humans …
The hepatitis E virus open reading frame 2 protein: beyond viral capsid
Z Zhou, Y Xie, C Wu, Y Nan - Frontiers in Microbiology, 2021 - frontiersin.org
Hepatitis E virus (HEV) is a zoonotic pathogen causing hepatitis in both human and animal
hosts, which is responsible for acute hepatitis E outbreaks worldwide. The 7.2 kb genome of …
hosts, which is responsible for acute hepatitis E outbreaks worldwide. The 7.2 kb genome of …
A comprehensive study of neutralizing antigenic sites on the hepatitis E virus (HEV) capsid by constructing, clustering, and characterizing a tool box
The hepatitis E virus (HEV) ORF2 encodes a single structural capsid protein. The E2s
domain (amino acids 459–606) of the capsid protein has been identified as the major …
domain (amino acids 459–606) of the capsid protein has been identified as the major …