A pharmacological update of ellagic acid

JL Ríos, RM Giner, M Marín, MC Recio - Planta medica, 2018 - thieme-connect.com
Ellagic acid is a common metabolite present in many medicinal plants and vegetables. It is
present either in free form or as part of more complex molecules (ellagitannins), which can …

Targeting arachidonic acid pathway by natural products for cancer prevention and therapy

NS Yarla, A Bishayee, G Sethi, P Reddanna… - Seminars in cancer …, 2016 - Elsevier
Arachidonic acid (AA) pathway, a metabolic process, plays a key role in carcinogenesis.
Hence, AA pathway metabolic enzymes phospholipase A 2 s (PLA 2 s), cyclooxygenases …

Novel antioxidants in food quality preservation and health promotion

F Shahidi, Y Zhong - European Journal of Lipid Science and …, 2010 - Wiley Online Library
Autoxidation in food and biological systems is responsible for a multitude of adverse effects
and implications in human health as well as in food stability and preservation. Antioxidants …

Bioavailability of phytochemicals and its enhancement by drug delivery systems

F Aqil, R Munagala, J Jeyabalan, MV Vadhanam - Cancer letters, 2013 - Elsevier
Issues of poor oral bioavailability of cancer chemopreventives have hindered progress in
cancer prevention. Novel delivery systems that modulate the pharmacokinetics of existing …

Technological and biotechnological processes to enhance the bioavailability of dietary (poly) phenols in humans

F Polia, M Pastor-Belda… - Journal of agricultural …, 2022 - ACS Publications
The health effects of (poly) phenols (PPs) depend upon their bioavailability that, in general,
is very low and shows a high interindividual variability. The low bioavailability of PPs is …

Recent advances and future prospects of phyto-phospholipid complexation technique for improving pharmacokinetic profile of plant actives

J Khan, A Alexander, S Saraf, S Saraf - Journal of controlled release, 2013 - Elsevier
The phyto-phospholipid complexation technique has emerged as one of the leading
methods of improving bioavailability of phytopharmaceuticals having poor competency of …

Bioavailability challenges associated with development of anti-cancer phenolics

S Gao, M Hu - Mini reviews in medicinal chemistry, 2010 - ingentaconnect.com
Phenolics including many polyphenols and flavonoids have the potentials to become
chemoprevention and chemotherapy agents. However, poor bioavailability limits their …

Current applications of solid lipid nanoparticles and nanostructured lipid carriers as vehicles in oral delivery systems for antioxidant nutraceuticals: A review

M Gunawan, V Boonkanokwong - Colloids and Surfaces B: Biointerfaces, 2024 - Elsevier
Antioxidant nutraceuticals can be found in several dietary sources and have been utilized for
various medical benefits including health promotion, disease prevention, and support for …

Drug complexes: perspective from academic research and pharmaceutical market

SR Munnangi, AAA Youssef, N Narala… - Pharmaceutical …, 2023 - Springer
Despite numerous research efforts, drug delivery through the oral route remains a major
challenge to formulation scientists. The oral delivery of drugs poses a significant challenge …

In vitro wound healing and cytotoxic effects of sinigrin–phytosome complex

A Mazumder, A Dwivedi, JL Du Preez… - International journal of …, 2016 - Elsevier
Sinigrin is a class of glucosinolates found naturally in plants of the Brassicaceae family.
Lately, studies have shown that sinigrin possesses anticancer, antibacterial and anti …