Musculoskeletal research should synergistically investigate bone and muscle to inform
approaches for maintaining mobility and to avoid bone fractures. The relationship between …

Amyotrophic lateral sclerosis (ALS), a devastating neurodegenerative disease, is
characterized by progressive motor neuron degeneration, leading to widespread weakness …

Throughout a vertebrate organism's lifespan, skeletal muscle mass and function
progressively decline. This age-related condition is termed sarcopenia. In humans …

PM 2.5 is known to induce lung injury, but its toxic effects on lung regenerative machinery
and the underlying mechanisms remain unknown. In this study, primary mouse alveolar type …

Ageing is the greatest risk factor for a multitude of age-related diseases including
sarcopenia-the loss of skeletal muscle mass and strength-which occurs at remarkable rates …

Skeletal muscular diseases predominantly affect skeletal and cardiac muscle, resulting in
muscle weakness, impaired respiratory function and decreased lifespan. These harmful …

Zebrafish (Danio rerio) have emerged as a valuable model organism for investigating
musculoskeletal development and the pathophysiology of associated diseases. Key genes …

Many age-related neurological diseases still lack effective treatments, making their
understanding a critical and urgent issue in the globally aging society. To overcome this …

Age-dependent loss of muscle mass and function is associated with oxidative stress. DJ-
1/Park7 acts as an antioxidant through multiple signalling pathways. DJ-1-knockout …

Electroporation (EP) stands out as a promising non-viral plasmid delivery strategy, although
achieving optimal transfection efficiency in vivo remains a challenge. A noteworthy …